PDCD7 protein (Homo sapiens) - STRING network view

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PDCD7

programmed cell death 7; Promotes apoptosis when overexpressed (By similarity) (485 aa)

Predicted Functional Partners:

RPA1

0.666

SNRNP200

0.644

C16orf59

0.499

FEZ2

0.491

UBC

0.483

GALE

0.472

ABCA4

0.472

FEZ1

0.470

RIPK1

0.430

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA4	PDCD7	ENSP00000359245	ENSP00000204549	ATP-binding cassette, sub-family A (ABC1), member 4; In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans- retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removi [...]	programmed cell death 7; Promotes apoptosis when overexpressed (By similarity)	0.472
ABCA4	RPA1	ENSP00000359245	ENSP00000254719	ATP-binding cassette, sub-family A (ABC1), member 4; In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans- retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removi [...]	replication protein A1, 70kDa; Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing	0.420
C16orf59	FEZ1	ENSP00000355022	ENSP00000278919	chromosome 16 open reading frame 59	fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules	0.443
C16orf59	FEZ2	ENSP00000355022	ENSP00000368547	chromosome 16 open reading frame 59	fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity)	0.654
C16orf59	PDCD7	ENSP00000355022	ENSP00000204549	chromosome 16 open reading frame 59	programmed cell death 7; Promotes apoptosis when overexpressed (By similarity)	0.499
FEZ1	C16orf59	ENSP00000278919	ENSP00000355022	fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules	chromosome 16 open reading frame 59	0.443
FEZ1	FEZ2	ENSP00000278919	ENSP00000368547	fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules	fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity)	0.486
FEZ1	PDCD7	ENSP00000278919	ENSP00000204549	fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules	programmed cell death 7; Promotes apoptosis when overexpressed (By similarity)	0.470
FEZ1	UBC	ENSP00000278919	ENSP00000344818	fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules	ubiquitin C	0.576
FEZ2	C16orf59	ENSP00000368547	ENSP00000355022	fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity)	chromosome 16 open reading frame 59	0.654
FEZ2	FEZ1	ENSP00000368547	ENSP00000278919	fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity)	fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules	0.486
FEZ2	PDCD7	ENSP00000368547	ENSP00000204549	fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity)	programmed cell death 7; Promotes apoptosis when overexpressed (By similarity)	0.491
FEZ2	UBC	ENSP00000368547	ENSP00000344818	fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity)	ubiquitin C	0.483
GALE	PDCD7	ENSP00000363621	ENSP00000204549	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	programmed cell death 7; Promotes apoptosis when overexpressed (By similarity)	0.472
GALE	RPA1	ENSP00000363621	ENSP00000254719	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	replication protein A1, 70kDa; Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing	0.582
GALE	UBC	ENSP00000363621	ENSP00000344818	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	ubiquitin C	0.893
PDCD7	ABCA4	ENSP00000204549	ENSP00000359245	programmed cell death 7; Promotes apoptosis when overexpressed (By similarity)	ATP-binding cassette, sub-family A (ABC1), member 4; In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans- retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removi [...]	0.472
PDCD7	C16orf59	ENSP00000204549	ENSP00000355022	programmed cell death 7; Promotes apoptosis when overexpressed (By similarity)	chromosome 16 open reading frame 59	0.499
PDCD7	FEZ1	ENSP00000204549	ENSP00000278919	programmed cell death 7; Promotes apoptosis when overexpressed (By similarity)	fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules	0.470
PDCD7	FEZ2	ENSP00000204549	ENSP00000368547	programmed cell death 7; Promotes apoptosis when overexpressed (By similarity)	fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity)	0.491

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