node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AASDH | AASDHPPT | ENSP00000205214 | ENSP00000278618 | aminoadipate-semialdehyde dehydrogenase | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4’- phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN | 0.989 |
AASDH | AASS | ENSP00000205214 | ENSP00000377040 | aminoadipate-semialdehyde dehydrogenase | aminoadipate-semialdehyde synthase; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively | 0.896 |
AASDH | ACSM2B | ENSP00000205214 | ENSP00000327453 | aminoadipate-semialdehyde dehydrogenase | acyl-CoA synthetase medium-chain family member 2B; Has medium-chain fatty acid-CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) | 0.591 |
AASDH | ACSS1 | ENSP00000205214 | ENSP00000316924 | aminoadipate-semialdehyde dehydrogenase | acyl-CoA synthetase short-chain family member 1 | 0.536 |
AASDH | ACSS3 | ENSP00000205214 | ENSP00000449535 | aminoadipate-semialdehyde dehydrogenase | acyl-CoA synthetase short-chain family member 3; Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity) | 0.537 |
AASDH | C10orf129 | ENSP00000205214 | ENSP00000340296 | aminoadipate-semialdehyde dehydrogenase | chromosome 10 open reading frame 129 | 0.537 |
AASDH | DTNBP1 | ENSP00000205214 | ENSP00000341680 | aminoadipate-semialdehyde dehydrogenase | dystrobrevin binding protein 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 fun [...] | 0.610 |
AASDH | KIAA0368 | ENSP00000205214 | ENSP00000259335 | aminoadipate-semialdehyde dehydrogenase | KIAA0368; Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and other enhanced proteolyis | 0.565 |
AASDH | SAMM50 | ENSP00000205214 | ENSP00000345445 | aminoadipate-semialdehyde dehydrogenase | sorting and assembly machinery component 50 homolog (S. cerevisiae); May be required for the assembly pathway of mitochondrial outer membrane proteins (By similarity) | 0.946 |
AASDH | SUPT3H | ENSP00000205214 | ENSP00000360515 | aminoadipate-semialdehyde dehydrogenase | suppressor of Ty 3 homolog (S. cerevisiae); Probable transcriptional activator | 0.566 |
AASDHPPT | AASDH | ENSP00000278618 | ENSP00000205214 | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4’- phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN | aminoadipate-semialdehyde dehydrogenase | 0.989 |
AASDHPPT | AASS | ENSP00000278618 | ENSP00000377040 | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4’- phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN | aminoadipate-semialdehyde synthase; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively | 0.877 |
AASS | AASDH | ENSP00000377040 | ENSP00000205214 | aminoadipate-semialdehyde synthase; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively | aminoadipate-semialdehyde dehydrogenase | 0.896 |
AASS | AASDHPPT | ENSP00000377040 | ENSP00000278618 | aminoadipate-semialdehyde synthase; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4’- phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN | 0.877 |
ACSM2B | AASDH | ENSP00000327453 | ENSP00000205214 | acyl-CoA synthetase medium-chain family member 2B; Has medium-chain fatty acid-CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) | aminoadipate-semialdehyde dehydrogenase | 0.591 |
ACSS1 | AASDH | ENSP00000316924 | ENSP00000205214 | acyl-CoA synthetase short-chain family member 1 | aminoadipate-semialdehyde dehydrogenase | 0.536 |
ACSS1 | ACSS3 | ENSP00000316924 | ENSP00000449535 | acyl-CoA synthetase short-chain family member 1 | acyl-CoA synthetase short-chain family member 3; Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity) | 0.915 |
ACSS3 | AASDH | ENSP00000449535 | ENSP00000205214 | acyl-CoA synthetase short-chain family member 3; Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity) | aminoadipate-semialdehyde dehydrogenase | 0.537 |
ACSS3 | ACSS1 | ENSP00000449535 | ENSP00000316924 | acyl-CoA synthetase short-chain family member 3; Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity) | acyl-CoA synthetase short-chain family member 1 | 0.915 |
C10orf129 | AASDH | ENSP00000340296 | ENSP00000205214 | chromosome 10 open reading frame 129 | aminoadipate-semialdehyde dehydrogenase | 0.537 |