node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGXT2L1 | TEKT2 | ENSP00000296486 | ENSP00000207457 | alanine-glyoxylate aminotransferase 2-like 1; Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde | tektin 2 (testicular); Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) | 0.485 |
AGXT2L2 | TEKT2 | ENSP00000310978 | ENSP00000207457 | alanine-glyoxylate aminotransferase 2-like 2; Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde | tektin 2 (testicular); Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) | 0.485 |
C2orf88 | TEKT2 | ENSP00000345107 | ENSP00000207457 | chromosome 2 open reading frame 88; Binds to type I regulatory subunits of protein kinase A (PKA-RI) and may anchor/target them to the plasma membrane | tektin 2 (testicular); Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) | 0.483 |
CCDC172 | TEKT2 | ENSP00000329860 | ENSP00000207457 | coiled-coil domain containing 172 | tektin 2 (testicular); Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) | 0.586 |
DNAH11 | DNAH5 | ENSP00000330671 | ENSP00000265104 | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | 0.477 |
DNAH11 | DNAI1 | ENSP00000330671 | ENSP00000242317 | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | 0.855 |
DNAH11 | SPAG6 | ENSP00000330671 | ENSP00000365811 | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | sperm associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility (By similarity) | 0.487 |
DNAH11 | TEKT2 | ENSP00000330671 | ENSP00000207457 | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | tektin 2 (testicular); Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) | 0.497 |
DNAH5 | DNAH11 | ENSP00000265104 | ENSP00000330671 | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | 0.477 |
DNAH5 | DNAI1 | ENSP00000265104 | ENSP00000242317 | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | 0.894 |
DNAH5 | SPAG6 | ENSP00000265104 | ENSP00000365811 | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | sperm associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility (By similarity) | 0.452 |
DNAH5 | TEKT2 | ENSP00000265104 | ENSP00000207457 | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | tektin 2 (testicular); Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) | 0.462 |
DNAI1 | DNAH11 | ENSP00000242317 | ENSP00000330671 | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | 0.855 |
DNAI1 | DNAH5 | ENSP00000242317 | ENSP00000265104 | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | 0.894 |
DNAI1 | SPAG6 | ENSP00000242317 | ENSP00000365811 | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | sperm associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility (By similarity) | 0.629 |
DNAI1 | TEKT2 | ENSP00000242317 | ENSP00000207457 | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | tektin 2 (testicular); Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) | 0.487 |
HSD17B2 | TEKT2 | ENSP00000199936 | ENSP00000207457 | hydroxysteroid (17-beta) dehydrogenase 2; Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH | tektin 2 (testicular); Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) | 0.487 |
SPAG6 | DNAH11 | ENSP00000365811 | ENSP00000330671 | sperm associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility (By similarity) | dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP | 0.487 |
SPAG6 | DNAH5 | ENSP00000365811 | ENSP00000265104 | sperm associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility (By similarity) | dynein, axonemal, heavy chain 5; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles | 0.452 |
SPAG6 | DNAI1 | ENSP00000365811 | ENSP00000242317 | sperm associated antigen 6; Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility (By similarity) | dynein, axonemal, intermediate chain 1; Part of the dynein complex of respiratory cilia | 0.629 |