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CYP4B1 CYP4B1 CMAHP CMAHP CYP2C9 CYP2C9 FMO2 FMO2 CYP2D6 CYP2D6 DECR1 DECR1 CYP3A4 CYP3A4 NRIP2 NRIP2
"FMO2" - flavin containing monooxygenase 2 in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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FMO2flavin containing monooxygenase 2 (non-functional); Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive (471 aa)    
Predicted Functional Partners:
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S- warfarin, diclofenac, phenytoin, tolbutamide and losartan (490 aa)
        score_image score_image score_image   0.925
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1’-hydroxylation and midazolam 4- hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2- exo-monooxygenase. The enzyme also hydroxylates etoposide (503 aa)
        score_image score_image score_image   0.925
CYP2D6
cytochrome P450, family 2, subfamily D, polypeptide 6; Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants (497 aa)
        score_image score_image score_image   0.924
CMAHP
cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene (501 aa)
            score_image   0.603
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial; Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA (335 aa)
            score_image   0.497
CYP4B1
cytochrome P450, family 4, subfamily B, polypeptide 1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (512 aa)
        score_image   score_image   0.456
NRIP2
nuclear receptor interacting protein 2; Down-regulates transcriptional activation by nuclear receptors such as NR1F2 (By similarity) (281 aa)
            score_image   0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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