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STRINGSTRING
ZNF764 ZNF764 SRPK2 SRPK2 CCDC159 CCDC159 EAF1 EAF1 PPP1R3D PPP1R3D OCEL1 OCEL1 EAF2 EAF2 ASAP2 ASAP2 PRR23A PRR23A TCEB2 TCEB2 CCDC9 CCDC9
"OCEL1" - occludin/ELL domain containing 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
OCEL1occludin/ELL domain containing 1 (264 aa)    
Predicted Functional Partners:
EAF1
ELL associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities (268 aa)
            score_image   0.698
EAF2
ELL associated factor 2; Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo (260 aa)
            score_image   0.698
TCEB2
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B); SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (161 aa)
            score_image   0.663
PPP1R3D
protein phosphatase 1, regulatory subunit 3D; Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis (299 aa)
            score_image   0.631
CCDC159
coiled-coil domain containing 159 (297 aa)
            score_image   0.561
PRR23A
proline rich 23A (266 aa)
            score_image   0.504
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration (1006 aa)
            score_image   0.492
ZNF764
zinc finger protein 764; May be involved in transcriptional regulation (408 aa)
            score_image   0.472
CCDC9
coiled-coil domain containing 9 (531 aa)
            score_image   0.471
SRPK2
SRSF protein kinase 2; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and [...] (699 aa)
        score_image       0.461
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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