node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASAP2 | OCEL1 | ENSP00000281419 | ENSP00000215061 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration | occludin/ELL domain containing 1 | 0.492 |
CCDC159 | OCEL1 | ENSP00000402239 | ENSP00000215061 | coiled-coil domain containing 159 | occludin/ELL domain containing 1 | 0.561 |
CCDC9 | OCEL1 | ENSP00000221922 | ENSP00000215061 | coiled-coil domain containing 9 | occludin/ELL domain containing 1 | 0.471 |
CCDC9 | PRR23A | ENSP00000221922 | ENSP00000372649 | coiled-coil domain containing 9 | proline rich 23A | 0.537 |
EAF1 | OCEL1 | ENSP00000380054 | ENSP00000215061 | ELL associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities | occludin/ELL domain containing 1 | 0.698 |
EAF2 | OCEL1 | ENSP00000273668 | ENSP00000215061 | ELL associated factor 2; Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo | occludin/ELL domain containing 1 | 0.698 |
OCEL1 | ASAP2 | ENSP00000215061 | ENSP00000281419 | occludin/ELL domain containing 1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration | 0.492 |
OCEL1 | CCDC159 | ENSP00000215061 | ENSP00000402239 | occludin/ELL domain containing 1 | coiled-coil domain containing 159 | 0.561 |
OCEL1 | CCDC9 | ENSP00000215061 | ENSP00000221922 | occludin/ELL domain containing 1 | coiled-coil domain containing 9 | 0.471 |
OCEL1 | EAF1 | ENSP00000215061 | ENSP00000380054 | occludin/ELL domain containing 1 | ELL associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities | 0.698 |
OCEL1 | EAF2 | ENSP00000215061 | ENSP00000273668 | occludin/ELL domain containing 1 | ELL associated factor 2; Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo | 0.698 |
OCEL1 | PPP1R3D | ENSP00000215061 | ENSP00000360035 | occludin/ELL domain containing 1 | protein phosphatase 1, regulatory subunit 3D; Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis | 0.631 |
OCEL1 | PRR23A | ENSP00000215061 | ENSP00000372649 | occludin/ELL domain containing 1 | proline rich 23A | 0.504 |
OCEL1 | SRPK2 | ENSP00000215061 | ENSP00000377262 | occludin/ELL domain containing 1 | SRSF protein kinase 2; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and [...] | 0.461 |
OCEL1 | TCEB2 | ENSP00000215061 | ENSP00000262306 | occludin/ELL domain containing 1 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B); SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) | 0.663 |
OCEL1 | ZNF764 | ENSP00000215061 | ENSP00000252797 | occludin/ELL domain containing 1 | zinc finger protein 764; May be involved in transcriptional regulation | 0.472 |
PPP1R3D | OCEL1 | ENSP00000360035 | ENSP00000215061 | protein phosphatase 1, regulatory subunit 3D; Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis | occludin/ELL domain containing 1 | 0.631 |
PRR23A | CCDC9 | ENSP00000372649 | ENSP00000221922 | proline rich 23A | coiled-coil domain containing 9 | 0.537 |
PRR23A | OCEL1 | ENSP00000372649 | ENSP00000215061 | proline rich 23A | occludin/ELL domain containing 1 | 0.504 |
SRPK2 | OCEL1 | ENSP00000377262 | ENSP00000215061 | SRSF protein kinase 2; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and [...] | occludin/ELL domain containing 1 | 0.461 |