node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAM57A | LZTR1 | ENSP00000312017 | ENSP00000215739 | family with sequence similarity 57, member A | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | 0.485 |
FKBP8 | LZTR1 | ENSP00000222308 | ENSP00000215739 | FK506 binding protein 8, 38kDa; Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | 0.421 |
FKBP8 | UBC | ENSP00000222308 | ENSP00000344818 | FK506 binding protein 8, 38kDa; Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis | ubiquitin C | 0.917 |
KLHL6 | LZTR1 | ENSP00000341342 | ENSP00000215739 | kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity) | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | 0.528 |
KLHL6 | UBC | ENSP00000341342 | ENSP00000344818 | kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity) | ubiquitin C | 0.634 |
LZTR1 | FAM57A | ENSP00000215739 | ENSP00000312017 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | family with sequence similarity 57, member A | 0.485 |
LZTR1 | FKBP8 | ENSP00000215739 | ENSP00000222308 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | FK506 binding protein 8, 38kDa; Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis | 0.421 |
LZTR1 | KLHL6 | ENSP00000215739 | ENSP00000341342 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity) | 0.528 |
LZTR1 | PAPOLG | ENSP00000215739 | ENSP00000238714 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | poly(A) polymerase gamma; Responsible for the post-transcriptional adenylation of the 3’-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA | 0.427 |
LZTR1 | TBX1 | ENSP00000215739 | ENSP00000331791 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | 0.743 |
LZTR1 | UBC | ENSP00000215739 | ENSP00000344818 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | ubiquitin C | 0.620 |
LZTR1 | ZBTB1 | ENSP00000215739 | ENSP00000378201 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | zinc finger and BTB domain containing 1; May be involved in transcriptional regulation | 0.463 |
LZTR1 | ZBTB34 | ENSP00000215739 | ENSP00000362551 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | zinc finger and BTB domain containing 34; May be a transcriptional repressor | 0.486 |
LZTR1 | ZBTB48 | ENSP00000215739 | ENSP00000366902 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | zinc finger and BTB domain containing 48; Binds to and regulates the J and/or S elements in MHC II promoter | 0.660 |
LZTR1 | ZBTB5 | ENSP00000215739 | ENSP00000307604 | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | zinc finger and BTB domain containing 5; May be involved in transcriptional regulation | 0.522 |
PAPOLG | LZTR1 | ENSP00000238714 | ENSP00000215739 | poly(A) polymerase gamma; Responsible for the post-transcriptional adenylation of the 3’-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | 0.427 |
PAPOLG | UBC | ENSP00000238714 | ENSP00000344818 | poly(A) polymerase gamma; Responsible for the post-transcriptional adenylation of the 3’-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA | ubiquitin C | 0.697 |
TBX1 | LZTR1 | ENSP00000331791 | ENSP00000215739 | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis | 0.743 |
UBC | FKBP8 | ENSP00000344818 | ENSP00000222308 | ubiquitin C | FK506 binding protein 8, 38kDa; Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis | 0.917 |
UBC | KLHL6 | ENSP00000344818 | ENSP00000341342 | ubiquitin C | kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity) | 0.634 |