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FKBP7 FKBP7 DNAJC10 DNAJC10 SEL1L SEL1L PCYOX1 PCYOX1 OS9 OS9 NENF NENF RPN1 RPN1 FOXRED2 FOXRED2 FKBP14 FKBP14 ERP27 ERP27 TXNDC16 TXNDC16
"FOXRED2" - FAD-dependent oxidoreductase domain containing 2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
FOXRED2FAD-dependent oxidoreductase domain containing 2; Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation (684 aa)    
Predicted Functional Partners:
OS9
osteosarcoma amplified 9, endoplasmic reticulum lectin (667 aa)
        score_image   score_image   0.926
TXNDC16
thioredoxin domain containing 16 (825 aa)
            score_image   0.889
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10 (793 aa)
        score_image   score_image   0.751
SEL1L
sel-1 suppressor of lin-12-like (C. elegans); May play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (794 aa)
        score_image   score_image   0.685
NENF
neudesin neurotrophic factor; Displays neurotrophic activity and activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT in primary cultured neurons. Does not have mitogenic activity in primary cultured astrocytes. May play a role on neuronal differentiation and may have a transient effect on neural cell proliferation in neural precursor cells. Neurotrophic activity is enhanced by binding to heme (By similarity) (172 aa)
        score_image   score_image   0.659
ERP27
endoplasmic reticulum protein 27 (273 aa)
            score_image   0.644
FKBP7
FK506 binding protein 7; PPIases accelerate the folding of proteins during protein synthesis (222 aa)
            score_image   0.638
PCYOX1
prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (505 aa)
            score_image   0.634
FKBP14
FK506 binding protein 14, 22 kDa; PPIases accelerate the folding of proteins during protein synthesis (211 aa)
            score_image   0.633
RPN1
ribophorin I; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (607 aa)
        score_image   score_image   0.604
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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