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STRINGSTRING
RBFOX3 RBFOX3 GAD2 GAD2 GAD1 GAD1 CHAT CHAT SST SST NPY NPY PVALB PVALB CCK CCK CALB2 CALB2 SDF4 SDF4 MYH14 MYH14
"PVALB" - parvalbumin in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
PVALBparvalbumin; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (110 aa)    
Predicted Functional Partners:
CALB2
calbindin 2; Calretinin is a calcium-binding protein which is abundant in auditory neurons (271 aa)
            score_image   0.943
GAD1
glutamate decarboxylase 1 (brain, 67kDa); Catalyzes the production of GABA (594 aa)
        score_image   score_image   0.877
SDF4
stromal cell derived factor 4 (362 aa)
            score_image   0.871
SST
somatostatin; Somatostatin inhibits the release of somatotropin (116 aa)
            score_image   0.822
MYH14
myosin, heavy chain 14, non-muscle (2036 aa)
        score_image   score_image   0.814
CHAT
choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses (748 aa)
            score_image   0.814
CCK
cholecystokinin; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion (115 aa)
            score_image   0.782
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Catalyzes the production of GABA (585 aa)
        score_image   score_image   0.739
NPY
neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone (97 aa)
            score_image   0.725
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3; RNA-binding protein that regulates alternative splicing events (By similarity) (312 aa)
            score_image   0.724
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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