node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACAA2 | ACAT1 | ENSP00000285093 | ENSP00000265838 | acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | 0.972 |
ACAA2 | ACLY | ENSP00000285093 | ENSP00000253792 | acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | 0.760 |
ACAA2 | ACO2 | ENSP00000285093 | ENSP00000216254 | acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | aconitase 2, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity) | 0.945 |
ACAA2 | CS | ENSP00000285093 | ENSP00000342056 | acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | citrate synthase | 0.869 |
ACAT1 | ACAA2 | ENSP00000265838 | ENSP00000285093 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | 0.972 |
ACAT1 | ACLY | ENSP00000265838 | ENSP00000253792 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | 0.779 |
ACAT1 | ACO2 | ENSP00000265838 | ENSP00000216254 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | aconitase 2, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity) | 0.943 |
ACAT1 | CS | ENSP00000265838 | ENSP00000342056 | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | citrate synthase | 0.942 |
ACLY | ACAA2 | ENSP00000253792 | ENSP00000285093 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | 0.760 |
ACLY | ACAT1 | ENSP00000253792 | ENSP00000265838 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | 0.779 |
ACLY | ACO2 | ENSP00000253792 | ENSP00000216254 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | aconitase 2, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity) | 0.963 |
ACLY | CS | ENSP00000253792 | ENSP00000342056 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | citrate synthase | 0.955 |
ACLY | IDH1 | ENSP00000253792 | ENSP00000260985 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | isocitrate dehydrogenase 1 (NADP+), soluble | 0.966 |
ACLY | IDH2 | ENSP00000253792 | ENSP00000331897 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | isocitrate dehydrogenase 2 (NADP+), mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex | 0.969 |
ACLY | IDH3A | ENSP00000253792 | ENSP00000299518 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | isocitrate dehydrogenase 3 (NAD+) alpha | 0.957 |
ACLY | IDH3B | ENSP00000253792 | ENSP00000370223 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | isocitrate dehydrogenase 3 (NAD+) beta | 0.955 |
ACLY | IDH3G | ENSP00000253792 | ENSP00000217901 | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | isocitrate dehydrogenase 3 (NAD+) gamma | 0.957 |
ACO2 | ACAA2 | ENSP00000216254 | ENSP00000285093 | aconitase 2, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity) | acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage | 0.945 |
ACO2 | ACAT1 | ENSP00000216254 | ENSP00000265838 | aconitase 2, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity) | acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism | 0.943 |
ACO2 | ACLY | ENSP00000216254 | ENSP00000253792 | aconitase 2, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity) | ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine | 0.963 |