node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GFPT1 | GNPDA1 | ENSP00000354347 | ENSP00000311876 | glutamine--fructose-6-phosphate transaminase 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | 0.436 |
GFPT1 | GNPNAT1 | ENSP00000354347 | ENSP00000216410 | glutamine--fructose-6-phosphate transaminase 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | glucosamine-phosphate N-acetyltransferase 1 | 0.960 |
GFPT1 | HK1 | ENSP00000354347 | ENSP00000384774 | glutamine--fructose-6-phosphate transaminase 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | hexokinase 1 | 0.906 |
GFPT1 | HK2 | ENSP00000354347 | ENSP00000290573 | glutamine--fructose-6-phosphate transaminase 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | hexokinase 2 | 0.919 |
GFPT1 | HK3 | ENSP00000354347 | ENSP00000292432 | glutamine--fructose-6-phosphate transaminase 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | hexokinase 3 (white cell) | 0.903 |
GFPT1 | HKDC1 | ENSP00000354347 | ENSP00000346643 | glutamine--fructose-6-phosphate transaminase 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | hexokinase domain containing 1 | 0.903 |
GFPT1 | PGM3 | ENSP00000354347 | ENSP00000425809 | glutamine--fructose-6-phosphate transaminase 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | phosphoglucomutase 3 | 0.752 |
GFPT2 | GNPNAT1 | ENSP00000253778 | ENSP00000216410 | glutamine-fructose-6-phosphate transaminase 2; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | glucosamine-phosphate N-acetyltransferase 1 | 0.956 |
GFPT2 | HK1 | ENSP00000253778 | ENSP00000384774 | glutamine-fructose-6-phosphate transaminase 2; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | hexokinase 1 | 0.903 |
GFPT2 | HK2 | ENSP00000253778 | ENSP00000290573 | glutamine-fructose-6-phosphate transaminase 2; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | hexokinase 2 | 0.903 |
GFPT2 | HK3 | ENSP00000253778 | ENSP00000292432 | glutamine-fructose-6-phosphate transaminase 2; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | hexokinase 3 (white cell) | 0.903 |
GFPT2 | HKDC1 | ENSP00000253778 | ENSP00000346643 | glutamine-fructose-6-phosphate transaminase 2; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | hexokinase domain containing 1 | 0.903 |
GFPT2 | PGM3 | ENSP00000253778 | ENSP00000425809 | glutamine-fructose-6-phosphate transaminase 2; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | phosphoglucomutase 3 | 0.719 |
GNPDA1 | GFPT1 | ENSP00000311876 | ENSP00000354347 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | glutamine--fructose-6-phosphate transaminase 1; Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins | 0.436 |
GNPDA1 | GNPNAT1 | ENSP00000311876 | ENSP00000216410 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | glucosamine-phosphate N-acetyltransferase 1 | 0.932 |
GNPDA1 | HK1 | ENSP00000311876 | ENSP00000384774 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | hexokinase 1 | 0.912 |
GNPDA1 | HK2 | ENSP00000311876 | ENSP00000290573 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | hexokinase 2 | 0.907 |
GNPDA1 | HK3 | ENSP00000311876 | ENSP00000292432 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | hexokinase 3 (white cell) | 0.907 |
GNPDA1 | HKDC1 | ENSP00000311876 | ENSP00000346643 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | hexokinase domain containing 1 | 0.907 |
GNPDA1 | NAGK | ENSP00000311876 | ENSP00000389087 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | N-acetylglucosamine kinase; Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway- although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity | 0.602 |