Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | EMC9 | ER membrane protein complex subunit 9 (208 aa) | ||||||||||||
Predicted Functional Partners:
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 | EMC2 | ER membrane protein complex subunit 2 (297 aa) |
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0.997 | ||||||||
 | EMC3 | ER membrane protein complex subunit 3 (261 aa) |
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0.972 | ||||||||
 | EMC1 | ER membrane protein complex subunit 1 (993 aa) |
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0.972 | ||||||||
 | EMC4 | ER membrane protein complex subunit 4; May mediate anti-apoptotic activity (183 aa) |
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0.971 | |||||||||
 | EMC6 | ER membrane protein complex subunit 6 (110 aa) |
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0.906 | |||||||||
 | EMC10 | ER membrane protein complex subunit 10 (262 aa) |
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0.900 | ||||||||||
 | MMGT1 | membrane magnesium transporter 1; Mediates Mg(2+) transport (By similarity) (131 aa) |
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0.900 | ||||||||||
 | EMC7 | ER membrane protein complex subunit 7 (242 aa) |
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0.900 | ||||||||||
 | EMC8 | ER membrane protein complex subunit 8 (210 aa) |
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0.900 | |||||||||
 | TESPA1 | thymocyte expressed, positive selection associated 1; Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes (521 aa) |
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0.534 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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