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CGNL1 CGNL1 GDAP1L1 GDAP1L1 FITM2 FITM2 CGN CGN GLIPR2 GLIPR2 R3HDML R3HDML GLIS3 GLIS3 TMEM163 TMEM163 KCNK16 KCNK16 GCC1 GCC1 ZFAND3 ZFAND3
"R3HDML" - R3H domain containing-like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R3HDMLR3H domain containing-like; Putative serine protease inhibitor (By similarity) (253 aa)    
Predicted Functional Partners:
GDAP1L1
ganglioside induced differentiation associated protein 1-like 1 (367 aa)
            score_image   0.752
CGN
cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier (1203 aa)
            score_image   0.648
FITM2
fat storage-inducing transmembrane protein 2; Plays an important role in lipid droplet accumulation. Plays a role in the regulation of cell morphology and cytoskeletal organization (262 aa)
            score_image   0.581
GLIPR2
GLI pathogenesis-related 2 (154 aa)
    score_image       score_image   0.520
KCNK16
potassium channel, subfamily K, member 16; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents (322 aa)
            score_image   0.505
GCC1
GRIP and coiled-coil domain containing 1; Probably involved in maintaining Golgi structure (775 aa)
            score_image   0.488
TMEM163
transmembrane protein 163; May bind zinc and other divalent cations and recruit them to vesicular organelles (By similarity) (289 aa)
            score_image   0.480
GLIS3
GLIS family zinc finger 3; Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5’-GACCACCCAC-3’ (By similarity) (930 aa)
            score_image   0.470
ZFAND3
zinc finger, AN1-type domain 3 (227 aa)
            score_image   0.469
CGNL1
cingulin-like 1; May be involved in anchoring the apical junctional complex, especially tight junctions, to actin-based cytoskeletons (By similarity) (1302 aa)
            score_image   0.455
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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