MYL12A protein (Homo sapiens) - STRING network view

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MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity) (171 aa)

Predicted Functional Partners:

MYH9

0.980

PPP1R12A

0.979

PPP1R12B

0.978

PPP1R12C

0.978

MYLK

0.975

MYH14

0.963

MYH10

0.957

UBC

0.948

ACTB

0.879

MYH11

0.860

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	MYH10	ENSP00000349960	ENSP00000269243	actin, beta	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	0.944
ACTB	MYH11	ENSP00000349960	ENSP00000379616	actin, beta	myosin, heavy chain 11, smooth muscle; Muscle contraction	0.981
ACTB	MYH14	ENSP00000349960	ENSP00000262269	actin, beta	myosin, heavy chain 14, non-muscle	0.959
ACTB	MYH9	ENSP00000349960	ENSP00000216181	actin, beta	myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping	0.978
ACTB	MYL12A	ENSP00000349960	ENSP00000217652	actin, beta	myosin, light chain 12A, regulatory, non-sarcomeric; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	0.879
ACTB	UBC	ENSP00000349960	ENSP00000344818	actin, beta	ubiquitin C	0.999
MYH10	ACTB	ENSP00000269243	ENSP00000349960	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	actin, beta	0.944
MYH10	MYH11	ENSP00000269243	ENSP00000379616	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	myosin, heavy chain 11, smooth muscle; Muscle contraction	0.900
MYH10	MYH14	ENSP00000269243	ENSP00000262269	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	myosin, heavy chain 14, non-muscle	0.901
MYH10	MYH9	ENSP00000269243	ENSP00000216181	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping	0.996
MYH10	MYL12A	ENSP00000269243	ENSP00000217652	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	myosin, light chain 12A, regulatory, non-sarcomeric; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	0.957
MYH10	PPP1R12A	ENSP00000269243	ENSP00000261207	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	protein phosphatase 1, regulatory subunit 12A; Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity	0.544
MYH10	PPP1R12B	ENSP00000269243	ENSP00000384496	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	protein phosphatase 1, regulatory subunit 12B	0.518
MYH10	PPP1R12C	ENSP00000269243	ENSP00000263433	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	protein phosphatase 1, regulatory subunit 12C; Regulates myosin phosphatase activity	0.518
MYH10	UBC	ENSP00000269243	ENSP00000344818	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	ubiquitin C	0.970
MYH11	ACTB	ENSP00000379616	ENSP00000349960	myosin, heavy chain 11, smooth muscle; Muscle contraction	actin, beta	0.981
MYH11	MYH10	ENSP00000379616	ENSP00000269243	myosin, heavy chain 11, smooth muscle; Muscle contraction	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	0.900
MYH11	MYH14	ENSP00000379616	ENSP00000262269	myosin, heavy chain 11, smooth muscle; Muscle contraction	myosin, heavy chain 14, non-muscle	0.902
MYH11	MYH9	ENSP00000379616	ENSP00000216181	myosin, heavy chain 11, smooth muscle; Muscle contraction	myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping	0.900
MYH11	MYL12A	ENSP00000379616	ENSP00000217652	myosin, heavy chain 11, smooth muscle; Muscle contraction	myosin, light chain 12A, regulatory, non-sarcomeric; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)	0.860

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