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STRINGSTRING
LY6H LY6H MRPL3 MRPL3 PDE6B PDE6B PLXDC1 PLXDC1 TULP1 TULP1 GLA GLA ATP13A2 ATP13A2 C2CD4A C2CD4A PAOX PAOX C2CD4B C2CD4B
"GLA" - galactosidase, alpha in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLAgalactosidase, alpha (429 aa)    
Predicted Functional Partners:
PAOX
polyamine oxidase (exo-N4-amino) (511 aa)
            score_image   0.589
C2CD4B
C2 calcium-dependent domain containing 4B; May be involved in inflammatory process. May regulate cell architecture and adhesion (364 aa)
            score_image   0.489
C2CD4A
C2 calcium-dependent domain containing 4A; May be involved in inflammatory process. May regulate cell architecture and adhesion (369 aa)
            score_image   0.487
LY6H
lymphocyte antigen 6 complex, locus H (161 aa)
            score_image   0.485
MRPL3
mitochondrial ribosomal protein L3 (348 aa)
            score_image   0.483
ATP13A2
ATPase type 13A2; May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity (1180 aa)
            score_image   0.461
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta; This protein participates in processes of transmission and amplification of the visual signal. Necessary for the formation of a functional phosphodiesterase holoenzyme (854 aa)
            score_image   0.412
PLXDC1
plexin domain containing 1; Plays a critical role in endothelial cell capillary morphogenesis (By similarity) (500 aa)
            score_image   0.408
TULP1
tubby like protein 1; Required for normal development of photoreceptor synapses. Required for normal photoreceptor function and for long- term survival of photoreceptor cells. Interacts with cytoskeleton proteins and may play a role in protein transport in photoreceptor cells (By similarity). Binds lipids, especially phosphatidylinositol 3-phosphate, phosphatidylinositol 4- phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-bisphosphate, phosphatidylserine and phosphatidic acid (in vitro) [...] (542 aa)
            score_image   0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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