| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANGPTL7 | ZNF263 | ENSP00000366015 | ENSP00000219069 | angiopoietin-like 7 | zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor | 0.523 |
| CLK2 | CLK3 | ENSP00000354856 | ENSP00000378505 | CDC-like kinase 2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphorylates PPP2R5B there [...] | CDC-like kinase 3; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells | 0.939 |
| CLK2 | ZNF263 | ENSP00000354856 | ENSP00000219069 | CDC-like kinase 2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphorylates PPP2R5B there [...] | zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor | 0.584 |
| CLK3 | CLK2 | ENSP00000378505 | ENSP00000354856 | CDC-like kinase 3; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells | CDC-like kinase 2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphorylates PPP2R5B there [...] | 0.939 |
| CLK3 | ZNF263 | ENSP00000378505 | ENSP00000219069 | CDC-like kinase 3; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells | zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor | 0.771 |
| FOXRED1 | GPRC5B | ENSP00000263578 | ENSP00000300571 | FAD-dependent oxidoreductase domain containing 1 | G protein-coupled receptor, family C, group 5, member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways | 0.540 |
| FOXRED1 | L3MBTL4 | ENSP00000263578 | ENSP00000284898 | FAD-dependent oxidoreductase domain containing 1 | l(3)mbt-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity) | 0.575 |
| FOXRED1 | PET112 | ENSP00000263578 | ENSP00000263985 | FAD-dependent oxidoreductase domain containing 1 | PET112 homolog (yeast); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) | 0.554 |
| FOXRED1 | ZNF263 | ENSP00000263578 | ENSP00000219069 | FAD-dependent oxidoreductase domain containing 1 | zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor | 0.552 |
| GPRC5B | FOXRED1 | ENSP00000300571 | ENSP00000263578 | G protein-coupled receptor, family C, group 5, member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways | FAD-dependent oxidoreductase domain containing 1 | 0.540 |
| GPRC5B | L3MBTL4 | ENSP00000300571 | ENSP00000284898 | G protein-coupled receptor, family C, group 5, member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways | l(3)mbt-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity) | 0.568 |
| GPRC5B | PET112 | ENSP00000300571 | ENSP00000263985 | G protein-coupled receptor, family C, group 5, member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways | PET112 homolog (yeast); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) | 0.568 |
| GPRC5B | ZNF263 | ENSP00000300571 | ENSP00000219069 | G protein-coupled receptor, family C, group 5, member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways | zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor | 0.506 |
| KDM2A | ZNF263 | ENSP00000432786 | ENSP00000219069 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor | 0.501 |
| L3MBTL4 | FOXRED1 | ENSP00000284898 | ENSP00000263578 | l(3)mbt-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity) | FAD-dependent oxidoreductase domain containing 1 | 0.575 |
| L3MBTL4 | GPRC5B | ENSP00000284898 | ENSP00000300571 | l(3)mbt-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity) | G protein-coupled receptor, family C, group 5, member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways | 0.568 |
| L3MBTL4 | PET112 | ENSP00000284898 | ENSP00000263985 | l(3)mbt-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity) | PET112 homolog (yeast); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) | 0.577 |
| L3MBTL4 | ZNF263 | ENSP00000284898 | ENSP00000219069 | l(3)mbt-like 4 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity) | zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor | 0.568 |
| MEFV | ZNF263 | ENSP00000219596 | ENSP00000219069 | Mediterranean fever; Probably controls the inflammatory response in myelomonocytic cells at the level of the cytoskeleton organization | zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor | 0.519 |
| PET112 | FOXRED1 | ENSP00000263985 | ENSP00000263578 | PET112 homolog (yeast); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) | FAD-dependent oxidoreductase domain containing 1 | 0.554 |
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