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STRINGSTRING
ICA1 ICA1 CMTM6 CMTM6 MYADM MYADM CMTM7 CMTM7 CKLF CKLF BCL2L13 BCL2L13 PLLP PLLP MS4A12 MS4A12 LRCH4 LRCH4 BCAS3 BCAS3 TMEM163 TMEM163
"PLLP" - plasmolipin in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Cooccurence
Coexpression
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[Homology]
Score
PLLPplasmolipin; Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity) (182 aa)    
Predicted Functional Partners:
MYADM
myeloid-associated differentiation marker (322 aa)
            score_image   0.862
CKLF
chemokine-like factor; May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10 (152 aa)
            score_image   0.741
CMTM6
CKLF-like MARVEL transmembrane domain containing 6 (183 aa)
            score_image   0.563
MS4A12
membrane-spanning 4-domains, subfamily A, member 12; May be involved in signal transduction as a component of a multimeric receptor complex (267 aa)
        score_image   score_image   0.559
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4 (683 aa)
            score_image   0.545
CMTM7
CKLF-like MARVEL transmembrane domain containing 7 (175 aa)
            score_image   0.544
BCAS3
breast carcinoma amplified sequence 3 (928 aa)
            score_image   0.510
BCL2L13
BCL2-like 13 (apoptosis facilitator); May promote the activation of caspase-3 and apoptosis (485 aa)
        score_image       0.508
ICA1
islet cell autoantigen 1, 69kDa; May play a role in neurotransmitter secretion (By similarity) (483 aa)
            score_image   0.506
TMEM163
transmembrane protein 163; May bind zinc and other divalent cations and recruit them to vesicular organelles (By similarity) (289 aa)
            score_image   0.491
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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