SETD6 protein (Homo sapiens) - STRING network view

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SETD6

SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity (473 aa)

Predicted Functional Partners:

RELA

0.970

SETD4

0.774

DNAJC8

0.773

CTTNBP2NL

0.675

SETD5

0.657

UBC

0.639

MTFR1

0.582

RPL36A

0.544

ENSG00000257529

0.519

RPL36AL

0.519

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTTNBP2NL	SETD6	ENSP00000271277	ENSP00000219315	CTTNBP2 N-terminal like	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	0.675
CTTNBP2NL	UBC	ENSP00000271277	ENSP00000344818	CTTNBP2 N-terminal like	ubiquitin C	0.483
DNAJC8	SETD6	ENSP00000263697	ENSP00000219315	DnaJ (Hsp40) homolog, subfamily C, member 8	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	0.773
DNAJC8	UBC	ENSP00000263697	ENSP00000344818	DnaJ (Hsp40) homolog, subfamily C, member 8	ubiquitin C	0.620
ENSG00000257529	SETD6	ENSP00000386655	ENSP00000219315	Uncharacterized protein	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	0.519
ENSG00000257529	UBC	ENSP00000386655	ENSP00000344818	Uncharacterized protein	ubiquitin C	0.479
MTFR1	SETD6	ENSP00000262146	ENSP00000219315	mitochondrial fission regulator 1; May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission (By similarity)	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	0.582
RELA	SETD6	ENSP00000384273	ENSP00000219315	v-rel reticuloendotheliosis viral oncogene homolog A (avian); NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most a [...]	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	0.970
RELA	UBC	ENSP00000384273	ENSP00000344818	v-rel reticuloendotheliosis viral oncogene homolog A (avian); NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most a [...]	ubiquitin C	0.999
RPL36A	SETD6	ENSP00000404375	ENSP00000219315	ribosomal protein L36a	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	0.544
RPL36A	UBC	ENSP00000404375	ENSP00000344818	ribosomal protein L36a	ubiquitin C	0.495
RPL36AL	SETD6	ENSP00000346012	ENSP00000219315	ribosomal protein L36a-like	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	0.519
RPL36AL	UBC	ENSP00000346012	ENSP00000344818	ribosomal protein L36a-like	ubiquitin C	0.799
SETD4	SETD5	ENSP00000329189	ENSP00000383939	SET domain containing 4	SET domain containing 5	0.816
SETD4	SETD6	ENSP00000329189	ENSP00000219315	SET domain containing 4	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	0.774
SETD4	UBC	ENSP00000329189	ENSP00000344818	SET domain containing 4	ubiquitin C	0.515
SETD5	SETD4	ENSP00000383939	ENSP00000329189	SET domain containing 5	SET domain containing 4	0.816
SETD5	SETD6	ENSP00000383939	ENSP00000219315	SET domain containing 5	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	0.657
SETD6	CTTNBP2NL	ENSP00000219315	ENSP00000271277	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	CTTNBP2 N-terminal like	0.675
SETD6	DNAJC8	ENSP00000219315	ENSP00000263697	SET domain containing 6; Protein-lysine N-methyltransferase that specifically monomethylates ’Lys-310’ of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity	DnaJ (Hsp40) homolog, subfamily C, member 8	0.773

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