WFDC1 protein (Homo sapiens) - STRING network view

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Score

WFDC1

WAP four-disulfide core domain 1; Has growth inhibitory activity (By similarity) (220 aa)

Predicted Functional Partners:

PTS

0.576

CHRNA10

0.436

CBFA2T3

0.416

ESD

0.404

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBFA2T3	WFDC1	ENSP00000268679	ENSP00000219454	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	WAP four-disulfide core domain 1; Has growth inhibitory activity (By similarity)	0.416
CHRNA10	WFDC1	ENSP00000250699	ENSP00000219454	cholinergic receptor, nicotinic, alpha 10 (neuronal); Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and red [...]	WAP four-disulfide core domain 1; Has growth inhibitory activity (By similarity)	0.436
ESD	WFDC1	ENSP00000367992	ENSP00000219454	esterase D; Serine hydrolase involved in the detoxification of formaldehyde	WAP four-disulfide core domain 1; Has growth inhibitory activity (By similarity)	0.404
PTS	WFDC1	ENSP00000280362	ENSP00000219454	6-pyruvoyltetrahydropterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6- pyruvoyl tetrahydropterin	WAP four-disulfide core domain 1; Has growth inhibitory activity (By similarity)	0.576
WFDC1	CBFA2T3	ENSP00000219454	ENSP00000268679	WAP four-disulfide core domain 1; Has growth inhibitory activity (By similarity)	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.416
WFDC1	CHRNA10	ENSP00000219454	ENSP00000250699	WAP four-disulfide core domain 1; Has growth inhibitory activity (By similarity)	cholinergic receptor, nicotinic, alpha 10 (neuronal); Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and red [...]	0.436
WFDC1	ESD	ENSP00000219454	ENSP00000367992	WAP four-disulfide core domain 1; Has growth inhibitory activity (By similarity)	esterase D; Serine hydrolase involved in the detoxification of formaldehyde	0.404
WFDC1	PTS	ENSP00000219454	ENSP00000280362	WAP four-disulfide core domain 1; Has growth inhibitory activity (By similarity)	6-pyruvoyltetrahydropterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6- pyruvoyl tetrahydropterin	0.576

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