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CRYL1 CRYL1 SLC17A8 SLC17A8 PLOD2 PLOD2 PMM1 PMM1 SSTR1 SSTR1 CRYM CRYM ALDH18A1 ALDH18A1 CRYBB1 CRYBB1 DECR1 DECR1 CRYBA1 CRYBA1 L3HYPDH L3HYPDH
"CRYM" - crystallin, mu in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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CRYMcrystallin, mu; Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (314 aa)    
Predicted Functional Partners:
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial; Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA (335 aa)
            score_image   0.863
SLC17A8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate (589 aa)
            score_image   0.641
PMM1
phosphomannomutase 1; Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain (262 aa)
            score_image   0.606
CRYBB1
crystallin, beta B1; Crystallins are the dominant structural components of the vertebrate eye lens (252 aa)
            score_image   0.587
CRYL1
crystallin, lambda 1 (319 aa)
            score_image   0.585
ALDH18A1
aldehyde dehydrogenase 18 family, member A1 (795 aa)
            score_image   0.555
L3HYPDH
L-3-hydroxyproline dehydratase (trans-); Catalyzes the dehydration of trans-3-hydroxy-L-proline to delta-1-pyrroline-2-carboxylate (Pyr2C). May be required to degrade trans-3-hydroxy-L-proline from the diet and originating from the degradation of proteins such as collagen-IV that contain it (354 aa)
score_image   score_image           0.510
CRYBA1
crystallin, beta A1; Crystallins are the dominant structural components of the vertebrate eye lens (215 aa)
            score_image   0.493
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (758 aa)
        score_image   score_image   0.490
SSTR1
somatostatin receptor 1; Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins (391 aa)
            score_image   0.489
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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