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STRINGSTRING
GK5 GK5 GCG GCG GK GK GPD2 GPD2 GK2 GK2 AQP8 AQP8 SHPK SHPK SOD2 SOD2 AQP10 AQP10 AQP12A AQP12A AQP11 AQP11
"AQP8" - aquaporin 8 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
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Experiments
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Textmining
[Homology]
Score
AQP8aquaporin 8; Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea (261 aa)    
Predicted Functional Partners:
AQP10
aquaporin 10; Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol (301 aa)
    score_image       score_image   0.917
SOD2
superoxide dismutase 2, mitochondrial; Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) (222 aa)
          score_image score_image   0.910
GCG
glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life (180 aa)
            score_image   0.860
GK
glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism (553 aa)
score_image     score_image     score_image   0.814
GK5
glycerol kinase 5 (putative) (529 aa)
score_image     score_image     score_image   0.779
GK2
glycerol kinase 2; Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) (553 aa)
score_image     score_image     score_image   0.779
SHPK
sedoheptulokinase; Acts as a modulator of macrophage activation through control of glucose metabolism (By similarity) (478 aa)
score_image     score_image     score_image   0.779
AQP11
aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity) (271 aa)
            score_image   0.768
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial) (727 aa)
score_image     score_image     score_image   0.672
AQP12A
aquaporin 12A; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity) (295 aa)
            score_image   0.668
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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