DNAJC17 protein (Homo sapiens) - STRING network view

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Score

DNAJC17

DnaJ (Hsp40) homolog, subfamily C, member 17 (304 aa)

Predicted Functional Partners:

CDC5L

0.951

HSPA1L

0.794

RPUSD2

0.779

HSPA4L

0.777

HSPA14

0.742

HSPA1A

0.742

HSPA1B

0.742

HSPA12A

0.742

HSPA5

0.742

HSPA6

0.742

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC5L	DNAJC17	ENSP00000360532	ENSP00000220496	CDC5 cell division cycle 5-like (S. pombe); DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing	DnaJ (Hsp40) homolog, subfamily C, member 17	0.951
DNAJC17	CDC5L	ENSP00000220496	ENSP00000360532	DnaJ (Hsp40) homolog, subfamily C, member 17	CDC5 cell division cycle 5-like (S. pombe); DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing	0.951
DNAJC17	HSPA12A	ENSP00000220496	ENSP00000358211	DnaJ (Hsp40) homolog, subfamily C, member 17	heat shock 70kDa protein 12A	0.742
DNAJC17	HSPA14	ENSP00000220496	ENSP00000367623	DnaJ (Hsp40) homolog, subfamily C, member 17	heat shock 70kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity	0.742
DNAJC17	HSPA1A	ENSP00000220496	ENSP00000364802	DnaJ (Hsp40) homolog, subfamily C, member 17	heat shock 70kDa protein 1A	0.742
DNAJC17	HSPA1B	ENSP00000220496	ENSP00000364801	DnaJ (Hsp40) homolog, subfamily C, member 17	heat shock 70kDa protein 1B	0.742
DNAJC17	HSPA1L	ENSP00000220496	ENSP00000364805	DnaJ (Hsp40) homolog, subfamily C, member 17	heat shock 70kDa protein 1-like	0.794
DNAJC17	HSPA4L	ENSP00000220496	ENSP00000296464	DnaJ (Hsp40) homolog, subfamily C, member 17	heat shock 70kDa protein 4-like; Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase (By similarity)	0.777
DNAJC17	HSPA5	ENSP00000220496	ENSP00000324173	DnaJ (Hsp40) homolog, subfamily C, member 17	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER	0.742
DNAJC17	HSPA6	ENSP00000220496	ENSP00000310219	DnaJ (Hsp40) homolog, subfamily C, member 17	heat shock 70kDa protein 6 (HSP70B’); In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity)	0.742
DNAJC17	RPUSD2	ENSP00000220496	ENSP00000323288	DnaJ (Hsp40) homolog, subfamily C, member 17	RNA pseudouridylate synthase domain containing 2	0.779
HSPA12A	DNAJC17	ENSP00000358211	ENSP00000220496	heat shock 70kDa protein 12A	DnaJ (Hsp40) homolog, subfamily C, member 17	0.742
HSPA12A	HSPA1A	ENSP00000358211	ENSP00000364802	heat shock 70kDa protein 12A	heat shock 70kDa protein 1A	0.606
HSPA12A	HSPA4L	ENSP00000358211	ENSP00000296464	heat shock 70kDa protein 12A	heat shock 70kDa protein 4-like; Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase (By similarity)	0.756
HSPA14	DNAJC17	ENSP00000367623	ENSP00000220496	heat shock 70kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity	DnaJ (Hsp40) homolog, subfamily C, member 17	0.742
HSPA14	HSPA4L	ENSP00000367623	ENSP00000296464	heat shock 70kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity	heat shock 70kDa protein 4-like; Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase (By similarity)	0.455
HSPA1A	DNAJC17	ENSP00000364802	ENSP00000220496	heat shock 70kDa protein 1A	DnaJ (Hsp40) homolog, subfamily C, member 17	0.742
HSPA1A	HSPA12A	ENSP00000364802	ENSP00000358211	heat shock 70kDa protein 1A	heat shock 70kDa protein 12A	0.606
HSPA1A	HSPA4L	ENSP00000364802	ENSP00000296464	heat shock 70kDa protein 1A	heat shock 70kDa protein 4-like; Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase (By similarity)	0.550
HSPA1B	DNAJC17	ENSP00000364801	ENSP00000220496	heat shock 70kDa protein 1B	DnaJ (Hsp40) homolog, subfamily C, member 17	0.742

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