| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALB | B2M | ENSP00000295897 | ENSP00000452780 | albumin | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | 0.730 |
| ALB | FCGRT | ENSP00000295897 | ENSP00000221466 | albumin | Fc fragment of IgG, receptor, transporter, alpha; Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus | 0.997 |
| B2M | ALB | ENSP00000452780 | ENSP00000295897 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | albumin | 0.730 |
| B2M | FCGR1A | ENSP00000452780 | ENSP00000358165 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | Fc fragment of IgG, high affinity Ia, receptor (CD64) | 0.585 |
| B2M | FCGR1B | ENSP00000452780 | ENSP00000358391 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | Fc fragment of IgG, high affinity Ib, receptor (CD64); May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response | 0.585 |
| B2M | FCGR2A | ENSP00000452780 | ENSP00000271450 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | 0.647 |
| B2M | FCGR2B | ENSP00000452780 | ENSP00000351497 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | Fc fragment of IgG, low affinity IIb, receptor (CD32); Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis | 0.606 |
| B2M | FCGR3A | ENSP00000452780 | ENSP00000356946 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | 0.649 |
| B2M | FCGRT | ENSP00000452780 | ENSP00000221466 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | Fc fragment of IgG, receptor, transporter, alpha; Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus | 0.977 |
| B2M | PDIA3 | ENSP00000452780 | ENSP00000300289 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | protein disulfide isomerase family A, member 3 | 0.921 |
| CA6 | FCGRT | ENSP00000366662 | ENSP00000221466 | carbonic anhydrase VI; Reversible hydration of carbon dioxide. Its role in saliva is unknown | Fc fragment of IgG, receptor, transporter, alpha; Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus | 0.576 |
| FCGR1A | B2M | ENSP00000358165 | ENSP00000452780 | Fc fragment of IgG, high affinity Ia, receptor (CD64) | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | 0.585 |
| FCGR1A | FCGR3A | ENSP00000358165 | ENSP00000356946 | Fc fragment of IgG, high affinity Ia, receptor (CD64) | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | 0.653 |
| FCGR1A | FCGRT | ENSP00000358165 | ENSP00000221466 | Fc fragment of IgG, high affinity Ia, receptor (CD64) | Fc fragment of IgG, receptor, transporter, alpha; Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus | 0.585 |
| FCGR1B | B2M | ENSP00000358391 | ENSP00000452780 | Fc fragment of IgG, high affinity Ib, receptor (CD64); May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | 0.585 |
| FCGR1B | FCGRT | ENSP00000358391 | ENSP00000221466 | Fc fragment of IgG, high affinity Ib, receptor (CD64); May bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response | Fc fragment of IgG, receptor, transporter, alpha; Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus | 0.585 |
| FCGR2A | B2M | ENSP00000271450 | ENSP00000452780 | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | 0.647 |
| FCGR2A | FCGR3A | ENSP00000271450 | ENSP00000356946 | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis | 0.916 |
| FCGR2A | FCGRT | ENSP00000271450 | ENSP00000221466 | Fc fragment of IgG, low affinity IIa, receptor (CD32); Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens | Fc fragment of IgG, receptor, transporter, alpha; Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus | 0.697 |
| FCGR2B | B2M | ENSP00000351497 | ENSP00000452780 | Fc fragment of IgG, low affinity IIb, receptor (CD32); Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | 0.606 |
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