Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DUOX2 | DUOXA2 | ENSP00000373691 | ENSP00000319705 | dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain | dual oxidase maturation factor 2; Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis | 0.990 |
| DUOX2 | IYD | ENSP00000373691 | ENSP00000229447 | dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain | iodotyrosine deiodinase | 0.741 |
| DUOX2 | SLC26A4 | ENSP00000373691 | ENSP00000265715 | dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain | solute carrier family 26, member 4; Sodium-independent transporter of chloride and iodide | 0.581 |
| DUOX2 | SLC5A5 | ENSP00000373691 | ENSP00000222248 | dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain | solute carrier family 5 (sodium iodide symporter), member 5; Mediates iodide uptake in the thyroid gland | 0.745 |
| DUOX2 | TG | ENSP00000373691 | ENSP00000220616 | dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain | thyroglobulin | 0.580 |
| DUOX2 | TSHR | ENSP00000373691 | ENSP00000298171 | dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain | thyroid stimulating hormone receptor | 0.502 |
| DUOXA2 | DUOX2 | ENSP00000319705 | ENSP00000373691 | dual oxidase maturation factor 2; Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis | dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain | 0.990 |
| DUOXA2 | IYD | ENSP00000319705 | ENSP00000229447 | dual oxidase maturation factor 2; Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis | iodotyrosine deiodinase | 0.746 |
| DUOXA2 | SLC26A4 | ENSP00000319705 | ENSP00000265715 | dual oxidase maturation factor 2; Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis | solute carrier family 26, member 4; Sodium-independent transporter of chloride and iodide | 0.581 |
| DUOXA2 | SLC5A5 | ENSP00000319705 | ENSP00000222248 | dual oxidase maturation factor 2; Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis | solute carrier family 5 (sodium iodide symporter), member 5; Mediates iodide uptake in the thyroid gland | 0.742 |
| DUOXA2 | TG | ENSP00000319705 | ENSP00000220616 | dual oxidase maturation factor 2; Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis | thyroglobulin | 0.532 |
| DUOXA2 | TPO | ENSP00000319705 | ENSP00000318820 | dual oxidase maturation factor 2; Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis | thyroid peroxidase | 0.687 |
| IYD | DUOX2 | ENSP00000229447 | ENSP00000373691 | iodotyrosine deiodinase | dual oxidase 2; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain | 0.741 |
| IYD | DUOXA2 | ENSP00000229447 | ENSP00000319705 | iodotyrosine deiodinase | dual oxidase maturation factor 2; Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis | 0.746 |
| IYD | SLC26A4 | ENSP00000229447 | ENSP00000265715 | iodotyrosine deiodinase | solute carrier family 26, member 4; Sodium-independent transporter of chloride and iodide | 0.608 |
| IYD | SLC5A5 | ENSP00000229447 | ENSP00000222248 | iodotyrosine deiodinase | solute carrier family 5 (sodium iodide symporter), member 5; Mediates iodide uptake in the thyroid gland | 0.776 |
| IYD | TG | ENSP00000229447 | ENSP00000220616 | iodotyrosine deiodinase | thyroglobulin | 0.565 |
| IYD | TPO | ENSP00000229447 | ENSP00000318820 | iodotyrosine deiodinase | thyroid peroxidase | 0.958 |
| PRODH | SLC5A5 | ENSP00000349577 | ENSP00000222248 | proline dehydrogenase (oxidase) 1 | solute carrier family 5 (sodium iodide symporter), member 5; Mediates iodide uptake in the thyroid gland | 0.836 |
| PRODH2 | SLC5A5 | ENSP00000301175 | ENSP00000222248 | proline dehydrogenase (oxidase) 2; Converts proline to delta-1-pyrroline-5-carboxylate (Probable) | solute carrier family 5 (sodium iodide symporter), member 5; Mediates iodide uptake in the thyroid gland | 0.836 |
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