node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RAB3A | RAB3IP | ENSP00000222256 | ENSP00000447300 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | RAB3A interacting protein (rabin3) | 0.982 |
RAB3A | RIMS1 | ENSP00000222256 | ENSP00000428417 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | regulating synaptic membrane exocytosis 1 | 0.998 |
RAB3A | RIMS2 | ENSP00000222256 | ENSP00000384892 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | 0.995 |
RAB3A | RPH3A | ENSP00000222256 | ENSP00000374036 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | rabphilin 3A homolog (mouse); Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity) | 0.998 |
RAB3A | SLC17A7 | ENSP00000222256 | ENSP00000221485 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate | 0.932 |
RAB3A | SYN1 | ENSP00000222256 | ENSP00000295987 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level | 0.939 |
RAB3A | SYT1 | ENSP00000222256 | ENSP00000261205 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | synaptotagmin I; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2 | 0.980 |
RAB3A | SYTL4 | ENSP00000222256 | ENSP00000263033 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | synaptotagmin-like 4; Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner (By similarity) | 0.976 |
RAB3A | UNC13B | ENSP00000222256 | ENSP00000367756 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | unc-13 homolog B (C. elegans); Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) | 0.974 |
RAB3A | VAMP2 | ENSP00000222256 | ENSP00000314214 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | vesicle-associated membrane protein 2 (synaptobrevin 2); Involved in the targeting and/or fusion of transport vesicles to their target membrane | 0.975 |
RAB3IP | RAB3A | ENSP00000447300 | ENSP00000222256 | RAB3A interacting protein (rabin3) | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | 0.982 |
RAB3IP | RPH3A | ENSP00000447300 | ENSP00000374036 | RAB3A interacting protein (rabin3) | rabphilin 3A homolog (mouse); Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity) | 0.406 |
RIMS1 | RAB3A | ENSP00000428417 | ENSP00000222256 | regulating synaptic membrane exocytosis 1 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | 0.998 |
RIMS1 | SLC17A7 | ENSP00000428417 | ENSP00000221485 | regulating synaptic membrane exocytosis 1 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate | 0.931 |
RIMS1 | SYN1 | ENSP00000428417 | ENSP00000295987 | regulating synaptic membrane exocytosis 1 | synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level | 0.475 |
RIMS1 | SYT1 | ENSP00000428417 | ENSP00000261205 | regulating synaptic membrane exocytosis 1 | synaptotagmin I; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2 | 0.962 |
RIMS1 | UNC13B | ENSP00000428417 | ENSP00000367756 | regulating synaptic membrane exocytosis 1 | unc-13 homolog B (C. elegans); Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) | 0.999 |
RIMS1 | VAMP2 | ENSP00000428417 | ENSP00000314214 | regulating synaptic membrane exocytosis 1 | vesicle-associated membrane protein 2 (synaptobrevin 2); Involved in the targeting and/or fusion of transport vesicles to their target membrane | 0.941 |
RIMS2 | RAB3A | ENSP00000384892 | ENSP00000222256 | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | 0.995 |
RIMS2 | SYN1 | ENSP00000384892 | ENSP00000295987 | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | synapsin I; Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level | 0.427 |