USF2 protein (Homo sapiens) - STRING network view

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USF2

upstream transcription factor 2, c-fos interacting; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters (346 aa)

Predicted Functional Partners:

USF1

0.998

FOSL1

0.985

HMOX1

0.984

HOXB4

0.896

ALB

0.873

FSHR

0.866

HINT1

0.854

CYP19A1

0.841

SERPINE1

0.840

REN

0.836

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	CYP19A1	ENSP00000295897	ENSP00000260433	albumin	cytochrome P450, family 19, subfamily A, polypeptide 1; Catalyzes the formation of aromatic C18 estrogens from C19 androgens	0.538
ALB	HMOX1	ENSP00000295897	ENSP00000216117	albumin	heme oxygenase (decycling) 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed	0.645
ALB	REN	ENSP00000295897	ENSP00000272190	albumin	renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney	0.812
ALB	SERPINE1	ENSP00000295897	ENSP00000223095	albumin	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Serine protease inhibitor. This inhibitor acts as ’bait’ for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis	0.993
ALB	USF1	ENSP00000295897	ENSP00000356999	albumin	upstream transcription factor 1; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters	0.499
ALB	USF2	ENSP00000295897	ENSP00000222305	albumin	upstream transcription factor 2, c-fos interacting; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters	0.873
CYP19A1	ALB	ENSP00000260433	ENSP00000295897	cytochrome P450, family 19, subfamily A, polypeptide 1; Catalyzes the formation of aromatic C18 estrogens from C19 androgens	albumin	0.538
CYP19A1	FSHR	ENSP00000260433	ENSP00000384708	cytochrome P450, family 19, subfamily A, polypeptide 1; Catalyzes the formation of aromatic C18 estrogens from C19 androgens	follicle stimulating hormone receptor; Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase	0.822
CYP19A1	USF2	ENSP00000260433	ENSP00000222305	cytochrome P450, family 19, subfamily A, polypeptide 1; Catalyzes the formation of aromatic C18 estrogens from C19 androgens	upstream transcription factor 2, c-fos interacting; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters	0.841
FOSL1	HMOX1	ENSP00000310170	ENSP00000216117	FOS-like antigen 1	heme oxygenase (decycling) 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed	0.948
FOSL1	USF1	ENSP00000310170	ENSP00000356999	FOS-like antigen 1	upstream transcription factor 1; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters	0.848
FOSL1	USF2	ENSP00000310170	ENSP00000222305	FOS-like antigen 1	upstream transcription factor 2, c-fos interacting; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters	0.985
FSHR	CYP19A1	ENSP00000384708	ENSP00000260433	follicle stimulating hormone receptor; Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase	cytochrome P450, family 19, subfamily A, polypeptide 1; Catalyzes the formation of aromatic C18 estrogens from C19 androgens	0.822
FSHR	USF2	ENSP00000384708	ENSP00000222305	follicle stimulating hormone receptor; Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase	upstream transcription factor 2, c-fos interacting; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters	0.866
HINT1	USF2	ENSP00000304229	ENSP00000222305	histidine triad nucleotide binding protein 1; Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5’monophosphoramidate (AMP-NH2), adenosine 5’monophosphomorpholidate (AMP-morpholidate) and guanosine 5’monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His- AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5’-O-phosphorothioate and guan [...]	upstream transcription factor 2, c-fos interacting; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters	0.854
HMOX1	ALB	ENSP00000216117	ENSP00000295897	heme oxygenase (decycling) 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed	albumin	0.645
HMOX1	FOSL1	ENSP00000216117	ENSP00000310170	heme oxygenase (decycling) 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed	FOS-like antigen 1	0.948
HMOX1	SERPINE1	ENSP00000216117	ENSP00000223095	heme oxygenase (decycling) 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Serine protease inhibitor. This inhibitor acts as ’bait’ for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis	0.495
HMOX1	USF2	ENSP00000216117	ENSP00000222305	heme oxygenase (decycling) 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed	upstream transcription factor 2, c-fos interacting; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters	0.984
HOXB4	USF2	ENSP00000328928	ENSP00000222305	homeobox B4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	upstream transcription factor 2, c-fos interacting; Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5’-CACGTG-3’) that is found in a variety of viral and cellular promoters	0.896

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