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MAP1LC3B MAP1LC3B BLOC1S3 BLOC1S3 BLOC1S1 BLOC1S1 GABARAPL1 GABARAPL1 MAP1LC3A MAP1LC3A KXD1 KXD1 LRRC45 LRRC45 C17orf59 C17orf59 MCRS1 MCRS1 MYH7 MYH7 RUVBL2 RUVBL2
"KXD1" - KxDL motif containing 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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homology edge
protein homology
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Score
KXD1KxDL motif containing 1; Involved in endosomal cargo sorting (By similarity) (176 aa)    
Predicted Functional Partners:
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May negatively regulate aerobic respiration through mitochondrial prot [...] (153 aa)
      score_image score_image score_image score_image   0.781
RUVBL2
RuvB-like 2 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (5’ to 3’) activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity (463 aa)
        score_image       0.692
MCRS1
microspherule protein 1; Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (475 aa)
        score_image       0.692
GABARAPL1
GABA(A) receptor-associated protein like 1; Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles (117 aa)
        score_image   score_image   0.689
MYH7
myosin, heavy chain 7, cardiac muscle, beta (1935 aa)
        score_image       0.597
LRRC45
leucine rich repeat containing 45 (670 aa)
        score_image       0.597
BLOC1S3
biogenesis of lysosomal organelles complex-1, subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking (202 aa)
          score_image score_image   0.594
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha; Involved in formation of autophagosomal vacuoles (autophagosomes) (125 aa)
        score_image       0.594
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta; Involved in formation of autophagosomal vacuoles (autophagosomes) (125 aa)
        score_image       0.594
C17orf59
chromosome 17 open reading frame 59 (357 aa)
      score_image score_image   score_image   0.584
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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