CYP3A43 protein (Homo sapiens) - STRING network view

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CYP3A43

cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity (504 aa)

Predicted Functional Partners:

NR1I2

0.581

NR1I3

0.506

PPIG

0.461

CYB5A

0.440

PTGIS

0.437

KCNA3

0.416

ENSG00000258529

0.400

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYB5A	CYP3A43	ENSP00000341625	ENSP00000222382	cytochrome b5 type A (microsomal); Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	0.440
CYB5A	PPIG	ENSP00000341625	ENSP00000260970	cytochrome b5 type A (microsomal); Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases	peptidylprolyl isomerase G (cyclophilin G); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing	0.561
CYP3A43	CYB5A	ENSP00000222382	ENSP00000341625	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	cytochrome b5 type A (microsomal); Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases	0.440
CYP3A43	ENSG00000258529	ENSP00000222382	ENSP00000456645	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	Uncharacterized protein	0.400
CYP3A43	KCNA3	ENSP00000222382	ENSP00000358784	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	potassium voltage-gated channel, shaker-related subfamily, member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient	0.416
CYP3A43	NR1I2	ENSP00000222382	ENSP00000336528	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	nuclear receptor subfamily 1, group I, member 2	0.581
CYP3A43	NR1I3	ENSP00000222382	ENSP00000356958	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	nuclear receptor subfamily 1, group I, member 3	0.506
CYP3A43	PPIG	ENSP00000222382	ENSP00000260970	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	peptidylprolyl isomerase G (cyclophilin G); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing	0.461
CYP3A43	PTGIS	ENSP00000222382	ENSP00000244043	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	prostaglandin I2 (prostacyclin) synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2)	0.437
ENSG00000258529	CYP3A43	ENSP00000456645	ENSP00000222382	Uncharacterized protein	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	0.400
KCNA3	CYP3A43	ENSP00000358784	ENSP00000222382	potassium voltage-gated channel, shaker-related subfamily, member 3; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	0.416
NR1I2	CYP3A43	ENSP00000336528	ENSP00000222382	nuclear receptor subfamily 1, group I, member 2	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	0.581
NR1I2	PPIG	ENSP00000336528	ENSP00000260970	nuclear receptor subfamily 1, group I, member 2	peptidylprolyl isomerase G (cyclophilin G); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing	0.715
NR1I3	CYP3A43	ENSP00000356958	ENSP00000222382	nuclear receptor subfamily 1, group I, member 3	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	0.506
NR1I3	PPIG	ENSP00000356958	ENSP00000260970	nuclear receptor subfamily 1, group I, member 3	peptidylprolyl isomerase G (cyclophilin G); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing	0.635
PPIG	CYB5A	ENSP00000260970	ENSP00000341625	peptidylprolyl isomerase G (cyclophilin G); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing	cytochrome b5 type A (microsomal); Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases	0.561
PPIG	CYP3A43	ENSP00000260970	ENSP00000222382	peptidylprolyl isomerase G (cyclophilin G); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	0.461
PPIG	NR1I2	ENSP00000260970	ENSP00000336528	peptidylprolyl isomerase G (cyclophilin G); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing	nuclear receptor subfamily 1, group I, member 2	0.715
PPIG	NR1I3	ENSP00000260970	ENSP00000356958	peptidylprolyl isomerase G (cyclophilin G); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing	nuclear receptor subfamily 1, group I, member 3	0.635
PTGIS	CYP3A43	ENSP00000244043	ENSP00000222382	prostaglandin I2 (prostacyclin) synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2)	cytochrome P450, family 3, subfamily A, polypeptide 43; Exhibits low testosterone 6-beta-hydroxylase activity	0.437

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