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SPTLC3 SPTLC3 NPCDR1 NPCDR1 SPTLC1 SPTLC1 SPTLC2 SPTLC2 AADACL4 AADACL4 ABHD11 ABHD11 ABHD12 ABHD12 AADACL2 AADACL2 GCAT GCAT ALAS2 ALAS2 ALAS1 ALAS1
"ABHD11" - abhydrolase domain containing 11 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABHD11abhydrolase domain containing 11 (315 aa)    
Predicted Functional Partners:
AADACL4
arylacetamide deacetylase-like 4 (407 aa)
            score_image   0.803
AADACL2
arylacetamide deacetylase-like 2 (401 aa)
            score_image   0.767
NPCDR1
Nasopharyngeal carcinoma-related gene protein (106 aa)
            score_image   0.720
ABHD12
abhydrolase domain containing 12 (404 aa)
            score_image   0.643
SPTLC3
serine palmitoyltransferase, long chain base subunit 3; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, while the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference (552 aa)
score_image       score_image   score_image   0.601
GCAT
glycine C-acetyltransferase (445 aa)
score_image       score_image   score_image   0.601
ALAS2
aminolevulinate, delta-, synthase 2 (587 aa)
score_image       score_image   score_image   0.601
ALAS1
aminolevulinate, delta-, synthase 1 (640 aa)
score_image       score_image   score_image   0.601
SPTLC1
serine palmitoyltransferase, long chain base subunit 1; Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1- SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isoz [...] (473 aa)
score_image       score_image   score_image   0.601
SPTLC2
serine palmitoyltransferase, long chain base subunit 2; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate (562 aa)
score_image       score_image   score_image   0.601
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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