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TTLL6 TTLL6 TTLL13 TTLL13 TTC30B TTC30B CC2D2A CC2D2A B9D2 B9D2 LSM14A LSM14A CEP41 CEP41 B9D1 B9D1 TCTN2 TCTN2 FAM98A FAM98A FAM98C FAM98C
"CEP41" - centrosomal protein 41kDa in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP41centrosomal protein 41kDa (373 aa)    
Predicted Functional Partners:
TTLL6
tubulin tyrosine ligase-like family, member 6 (891 aa)
            score_image   0.776
FAM98C
family with sequence similarity 98, member C (349 aa)
            score_image   0.583
TTLL13
tubulin tyrosine ligase-like family, member 13; Polyglutamylase which preferentially modifies alpha- tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity) (459 aa)
            score_image   0.538
B9D2
B9 protein domain 2; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes (175 aa)
            score_image   0.538
TCTN2
tectonic family member 2; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity) (697 aa)
            score_image   0.534
LSM14A
LSM14A, SCD6 homolog A (S. cerevisiae); Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs (463 aa)
            score_image   0.510
TTC30B
tetratricopeptide repeat domain 30B; Required for polyglutamylation of axonemal tubulin (By similarity). Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity) (665 aa)
            score_image   0.501
FAM98A
family with sequence similarity 98, member A (518 aa)
            score_image   0.497
B9D1
B9 protein domain 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity) (204 aa)
            score_image   0.486
CC2D2A
coiled-coil and C2 domain containing 2A; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity) (1620 aa)
            score_image   0.455
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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