MYL7 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MYL7

myosin, light chain 7, regulatory (175 aa)

Predicted Functional Partners:

MYLK3

0.976

MYH14

0.931

PPP1R12B

0.922

PPP1R12C

0.919

PPP1R12A

0.919

MYH9

0.913

MYH10

0.908

HEPACAM

0.860

ACTB

0.851

MYLK

0.846

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	MYH10	ENSP00000349960	ENSP00000269243	actin, beta	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	0.944
ACTB	MYH14	ENSP00000349960	ENSP00000262269	actin, beta	myosin, heavy chain 14, non-muscle	0.959
ACTB	MYH9	ENSP00000349960	ENSP00000216181	actin, beta	myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping	0.978
ACTB	MYL7	ENSP00000349960	ENSP00000223364	actin, beta	myosin, light chain 7, regulatory	0.851
HEPACAM	MYL7	ENSP00000298251	ENSP00000223364	hepatic and glial cell adhesion molecule; Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation	myosin, light chain 7, regulatory	0.860
HEPACAM	MYLK3	ENSP00000298251	ENSP00000378288	hepatic and glial cell adhesion molecule; Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation	myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity)	0.812
MYH10	ACTB	ENSP00000269243	ENSP00000349960	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	actin, beta	0.944
MYH10	MYH14	ENSP00000269243	ENSP00000262269	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	myosin, heavy chain 14, non-muscle	0.901
MYH10	MYH9	ENSP00000269243	ENSP00000216181	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping	0.996
MYH10	MYL7	ENSP00000269243	ENSP00000223364	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	myosin, light chain 7, regulatory	0.908
MYH10	PPP1R12A	ENSP00000269243	ENSP00000261207	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	protein phosphatase 1, regulatory subunit 12A; Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity	0.544
MYH10	PPP1R12B	ENSP00000269243	ENSP00000384496	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	protein phosphatase 1, regulatory subunit 12B	0.518
MYH10	PPP1R12C	ENSP00000269243	ENSP00000263433	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	protein phosphatase 1, regulatory subunit 12C; Regulates myosin phosphatase activity	0.518
MYH14	ACTB	ENSP00000262269	ENSP00000349960	myosin, heavy chain 14, non-muscle	actin, beta	0.959
MYH14	MYH10	ENSP00000262269	ENSP00000269243	myosin, heavy chain 14, non-muscle	myosin, heavy chain 10, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2	0.901
MYH14	MYH9	ENSP00000262269	ENSP00000216181	myosin, heavy chain 14, non-muscle	myosin, heavy chain 9, non-muscle; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping	0.952
MYH14	MYL7	ENSP00000262269	ENSP00000223364	myosin, heavy chain 14, non-muscle	myosin, light chain 7, regulatory	0.931
MYH14	MYLK	ENSP00000262269	ENSP00000353452	myosin, heavy chain 14, non-muscle	myosin light chain kinase	0.982
MYH14	MYLK3	ENSP00000262269	ENSP00000378288	myosin, heavy chain 14, non-muscle	myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity)	0.965
MYH14	PPP1R12A	ENSP00000262269	ENSP00000261207	myosin, heavy chain 14, non-muscle	protein phosphatase 1, regulatory subunit 12A; Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity	0.968

page 1 of 4

Experiments

Cooccurrence

Databases

Neighborhood

Textmining

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About