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DNAH2 DNAH2 DNAH12 DNAH12 DNAH1 DNAH1 DNAH10 DNAH10 DYNC2H1 DYNC2H1 DNAH17 DNAH17 DNAH8 DNAH8 DYNC1H1 DYNC1H1 CLIP2 CLIP2 PLK1 PLK1 DNAH11 DNAH11
"CLIP2" - CAP-GLY domain containing linker protein 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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[Homology]
Score
CLIP2CAP-GLY domain containing linker protein 2 (1046 aa)    
Predicted Functional Partners:
PLK1
polo-like kinase 1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55 [...] (603 aa)
            score_image   0.643
DNAH1
dynein, axonemal, heavy chain 1 (4265 aa)
      score_image score_image   score_image   0.541
DNAH10
dynein, axonemal, heavy chain 10; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain (4471 aa)
      score_image score_image   score_image   0.541
DYNC2H1
dynein, cytoplasmic 2, heavy chain 1 (4314 aa)
      score_image score_image   score_image   0.541
DNAH17
dynein, axonemal, heavy chain 17; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) (4485 aa)
      score_image score_image   score_image   0.541
DNAH2
dynein, axonemal, heavy chain 2; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) (4427 aa)
      score_image score_image   score_image   0.541
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1; Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (4646 aa)
      score_image score_image   score_image   0.541
DNAH8
dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) (4695 aa)
      score_image score_image   score_image   0.541
DNAH11
dynein, axonemal, heavy chain 11; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (4523 aa)
      score_image score_image   score_image   0.541
DNAH12
dynein, axonemal, heavy chain 12 (457 aa)
      score_image score_image   score_image   0.541
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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