node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DAG1 | DMD | ENSP00000312435 | ENSP00000354923 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | dystrophin | 0.999 |
DAG1 | FKRP | ENSP00000312435 | ENSP00000326570 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | fukutin related protein; Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1) | 0.873 |
DAG1 | FKTN | ENSP00000312435 | ENSP00000223528 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | fukutin; May be a glycosyltransferase which participates in glycosylation of alpha-dystroglycan/DAG1. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development | 0.818 |
DAG1 | LAMA2 | ENSP00000312435 | ENSP00000400365 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | laminin, alpha 2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | 0.999 |
DAG1 | POMGNT1 | ENSP00000312435 | ENSP00000361052 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase; Participates in O-mannosyl glycosylation. May be responsible for the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O- Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins. Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity | 0.810 |
DAG1 | POMT1 | ENSP00000312435 | ENSP00000361302 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | protein-O-mannosyltransferase 1 | 0.949 |
DAG1 | POMT2 | ENSP00000312435 | ENSP00000261534 | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | protein-O-mannosyltransferase 2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient | 0.910 |
DMD | DAG1 | ENSP00000354923 | ENSP00000312435 | dystrophin | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | 0.999 |
DMD | FKRP | ENSP00000354923 | ENSP00000326570 | dystrophin | fukutin related protein; Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1) | 0.763 |
DMD | FKTN | ENSP00000354923 | ENSP00000223528 | dystrophin | fukutin; May be a glycosyltransferase which participates in glycosylation of alpha-dystroglycan/DAG1. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development | 0.642 |
DMD | LAMA2 | ENSP00000354923 | ENSP00000400365 | dystrophin | laminin, alpha 2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | 0.978 |
DMD | POMGNT1 | ENSP00000354923 | ENSP00000361052 | dystrophin | protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase; Participates in O-mannosyl glycosylation. May be responsible for the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O- Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins. Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity | 0.505 |
DMD | POMT1 | ENSP00000354923 | ENSP00000361302 | dystrophin | protein-O-mannosyltransferase 1 | 0.574 |
DMD | POMT2 | ENSP00000354923 | ENSP00000261534 | dystrophin | protein-O-mannosyltransferase 2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient | 0.511 |
DMD | TCAP | ENSP00000354923 | ENSP00000312624 | dystrophin | titin-cap; Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk | 0.948 |
FKRP | DAG1 | ENSP00000326570 | ENSP00000312435 | fukutin related protein; Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1) | dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization | 0.873 |
FKRP | DMD | ENSP00000326570 | ENSP00000354923 | fukutin related protein; Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1) | dystrophin | 0.763 |
FKRP | FKTN | ENSP00000326570 | ENSP00000223528 | fukutin related protein; Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1) | fukutin; May be a glycosyltransferase which participates in glycosylation of alpha-dystroglycan/DAG1. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development | 0.872 |
FKRP | LAMA2 | ENSP00000326570 | ENSP00000400365 | fukutin related protein; Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1) | laminin, alpha 2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components | 0.752 |
FKRP | POMGNT1 | ENSP00000326570 | ENSP00000361052 | fukutin related protein; Could be a transferase involved in the modification of glycan moieties of alpha-dystroglycan (DAG1) | protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase; Participates in O-mannosyl glycosylation. May be responsible for the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O- Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins. Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity | 0.870 |