| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DHX34 | TBC1D12 | ENSP00000331907 | ENSP00000225235 | DEAH (Asp-Glu-Ala-His) box polypeptide 34; Probable ATP-binding RNA helicase | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | 0.449 |
| LRRTM3 | TBC1D12 | ENSP00000355187 | ENSP00000225235 | leucine rich repeat transmembrane neuronal 3; Exhibits a limited synaptogenic activity in vitro, restricted to excitatory presynaptic differentiation (By similarity). May play a role in the development and maintenance of the vertebrate nervous system | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | 0.669 |
| LRRTM4 | TBC1D12 | ENSP00000386357 | ENSP00000225235 | leucine rich repeat transmembrane neuronal 4; May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation (By similarity) | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | 0.563 |
| RAB11A | RAB11B | ENSP00000261890 | ENSP00000333547 | RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...] | RAB11B, member RAS oncogene family; GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity) | 0.949 |
| RAB11A | TBC1D12 | ENSP00000261890 | ENSP00000225235 | RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...] | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | 0.463 |
| RAB11A | TBC1D20 | ENSP00000261890 | ENSP00000346139 | RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...] | TBC1 domain family, member 20; May act as a GTPase-activating protein for Rab family protein(s) | 0.433 |
| RAB11B | RAB11A | ENSP00000333547 | ENSP00000261890 | RAB11B, member RAS oncogene family; GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity) | RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...] | 0.949 |
| RAB11B | TBC1D12 | ENSP00000333547 | ENSP00000225235 | RAB11B, member RAS oncogene family; GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity) | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | 0.463 |
| TBC1D12 | DHX34 | ENSP00000225235 | ENSP00000331907 | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | DEAH (Asp-Glu-Ala-His) box polypeptide 34; Probable ATP-binding RNA helicase | 0.449 |
| TBC1D12 | LRRTM3 | ENSP00000225235 | ENSP00000355187 | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | leucine rich repeat transmembrane neuronal 3; Exhibits a limited synaptogenic activity in vitro, restricted to excitatory presynaptic differentiation (By similarity). May play a role in the development and maintenance of the vertebrate nervous system | 0.669 |
| TBC1D12 | LRRTM4 | ENSP00000225235 | ENSP00000386357 | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | leucine rich repeat transmembrane neuronal 4; May play a role in the development and maintenance of the vertebrate nervous system. Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation (By similarity) | 0.563 |
| TBC1D12 | RAB11A | ENSP00000225235 | ENSP00000261890 | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...] | 0.463 |
| TBC1D12 | RAB11B | ENSP00000225235 | ENSP00000333547 | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | RAB11B, member RAS oncogene family; GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity) | 0.463 |
| TBC1D12 | TBC1D20 | ENSP00000225235 | ENSP00000346139 | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | TBC1 domain family, member 20; May act as a GTPase-activating protein for Rab family protein(s) | 0.445 |
| TBC1D12 | TBC1D21 | ENSP00000225235 | ENSP00000300504 | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | TBC1 domain family, member 21; May act as a GTPase-activating protein for Rab family protein(s) | 0.531 |
| TBC1D12 | TBC1D7 | ENSP00000225235 | ENSP00000348813 | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | TBC1 domain family, member 7; Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is u [...] | 0.577 |
| TBC1D20 | RAB11A | ENSP00000346139 | ENSP00000261890 | TBC1 domain family, member 20; May act as a GTPase-activating protein for Rab family protein(s) | RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...] | 0.433 |
| TBC1D20 | TBC1D12 | ENSP00000346139 | ENSP00000225235 | TBC1 domain family, member 20; May act as a GTPase-activating protein for Rab family protein(s) | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | 0.445 |
| TBC1D20 | TBC1D21 | ENSP00000346139 | ENSP00000300504 | TBC1 domain family, member 20; May act as a GTPase-activating protein for Rab family protein(s) | TBC1 domain family, member 21; May act as a GTPase-activating protein for Rab family protein(s) | 0.561 |
| TBC1D21 | TBC1D12 | ENSP00000300504 | ENSP00000225235 | TBC1 domain family, member 21; May act as a GTPase-activating protein for Rab family protein(s) | TBC1 domain family, member 12; May act as a GTPase-activating protein for Rab family protein(s) | 0.531 |
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