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STRINGSTRING
PWP2 PWP2 WDR36 WDR36 ENSG00000248354 ENSG00000248354 CIRH1A CIRH1A HEATR1 HEATR1 TBL3 TBL3 UTP6 UTP6 UTP18 UTP18 WDR3 WDR3 NOL6 NOL6 UTP15 UTP15
UTP18 small subunit in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UTP18UTP18 small subunit (SSU) processome component homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (556 aa)    
Predicted Functional Partners:
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (597 aa)
      score_image score_image   score_image   0.999
PWP2
PWP2 periodic tryptophan protein homolog (yeast) (919 aa)
      score_image score_image   score_image   0.999
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (518 aa)
      score_image score_image   score_image   0.999
TBL3
transducin (beta)-like 3 (808 aa)
      score_image score_image   score_image   0.999
WDR36
WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2 (951 aa)
      score_image score_image   score_image   0.999
WDR3
WD repeat domain 3 (943 aa)
      score_image score_image   score_image   0.998
HEATR1
HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) (2144 aa)
      score_image score_image   score_image   0.995
ENSG00000248354
Uncharacterized protein (205 aa)
      score_image score_image   score_image   0.992
NOL6
nucleolar protein family 6 (RNA-associated) (1146 aa)
      score_image score_image   score_image   0.988
CIRH1A
cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV (686 aa)
      score_image score_image   score_image   0.985
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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