GALK1 protein (Homo sapiens) - STRING network view

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Score

GALK1

galactokinase 1; Major enzyme for galactose metabolism (392 aa)

Predicted Functional Partners:

GALT

0.999

GALM

0.998

GALE

0.996

ENSG00000258728

0.973

DHDH

0.875

RAD51

0.874

GALK2

0.825

UBC

0.767

LYPD4

0.756

TK1

0.751

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHDH	ENSG00000258728	ENSP00000221403	ENSP00000451792	dihydrodiol dehydrogenase (dimeric)	Uncharacterized protein	0.620
DHDH	GALE	ENSP00000221403	ENSP00000363621	dihydrodiol dehydrogenase (dimeric)	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	0.498
DHDH	GALK1	ENSP00000221403	ENSP00000225614	dihydrodiol dehydrogenase (dimeric)	galactokinase 1; Major enzyme for galactose metabolism	0.875
DHDH	GALK2	ENSP00000221403	ENSP00000453129	dihydrodiol dehydrogenase (dimeric)	galactokinase 2; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates	0.868
DHDH	GALT	ENSP00000221403	ENSP00000368119	dihydrodiol dehydrogenase (dimeric)	galactose-1-phosphate uridylyltransferase	0.629
ENSG00000258728	DHDH	ENSP00000451792	ENSP00000221403	Uncharacterized protein	dihydrodiol dehydrogenase (dimeric)	0.620
ENSG00000258728	GALE	ENSP00000451792	ENSP00000363621	Uncharacterized protein	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	0.992
ENSG00000258728	GALK1	ENSP00000451792	ENSP00000225614	Uncharacterized protein	galactokinase 1; Major enzyme for galactose metabolism	0.973
ENSG00000258728	GALK2	ENSP00000451792	ENSP00000453129	Uncharacterized protein	galactokinase 2; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates	0.973
ENSG00000258728	GALM	ENSP00000451792	ENSP00000272252	Uncharacterized protein	galactose mutarotase (aldose 1-epimerase); Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)	0.749
GALE	DHDH	ENSP00000363621	ENSP00000221403	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	dihydrodiol dehydrogenase (dimeric)	0.498
GALE	ENSG00000258728	ENSP00000363621	ENSP00000451792	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	Uncharacterized protein	0.992
GALE	GALK1	ENSP00000363621	ENSP00000225614	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	galactokinase 1; Major enzyme for galactose metabolism	0.996
GALE	GALK2	ENSP00000363621	ENSP00000453129	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	galactokinase 2; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates	0.988
GALE	GALM	ENSP00000363621	ENSP00000272252	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	galactose mutarotase (aldose 1-epimerase); Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)	0.959
GALE	GALT	ENSP00000363621	ENSP00000368119	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	galactose-1-phosphate uridylyltransferase	0.999
GALE	LYPD4	ENSP00000363621	ENSP00000328737	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	LY6/PLAUR domain containing 4	0.515
GALE	RAD51	ENSP00000363621	ENSP00000372088	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	RAD51 homolog (S. cerevisiae); Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3	0.739
GALE	UBC	ENSP00000363621	ENSP00000344818	UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine	ubiquitin C	0.893
GALK1	DHDH	ENSP00000225614	ENSP00000221403	galactokinase 1; Major enzyme for galactose metabolism	dihydrodiol dehydrogenase (dimeric)	0.875

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