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ADH6 ADH6 ACSS2 ACSS2 ADH1B ADH1B ACSS1 ACSS1 ADH1A ADH1A GSTA1 GSTA1 ALDH3A1 ALDH3A1 ADH5 ADH5 ADH4 ADH4 ADH7 ADH7 ABAT ABAT
"ALDH3A1" - aldehyde dehydrogenase 3 family, member A1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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white nodes:
second shell of interactors
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Known Interactions
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experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
ALDH3A1aldehyde dehydrogenase 3 family, member A1; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes (453 aa)    
Predicted Functional Partners:
ACSS1
acyl-CoA synthetase short-chain family member 1 (689 aa)
      score_image score_image score_image score_image   0.960
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide (375 aa)
          score_image score_image   0.960
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide; Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism (394 aa)
          score_image score_image   0.958
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide (375 aa)
          score_image score_image   0.957
ADH6
alcohol dehydrogenase 6 (class V) (375 aa)
          score_image score_image   0.955
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide (380 aa)
          score_image score_image   0.955
ACSS2
acyl-CoA synthetase short-chain family member 2; Activates acetate so that it can be used for lipid synthesis or for energy generation (714 aa)
      score_image score_image score_image score_image   0.952
ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide; Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (374 aa)
          score_image score_image   0.948
ABAT
4-aminobutyrate aminotransferase; Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (500 aa)
score_image     score_image score_image score_image score_image   0.943
GSTA1
glutathione S-transferase alpha 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (222 aa)
          score_image score_image   0.935
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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