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STRINGSTRING
SYNPR SYNPR FATE1 FATE1 SYNGR2 SYNGR2 TMC8 TMC8 VTI1A VTI1A TK1 TK1 UBC UBC CANX CANX TMC6 TMC6 SLC2A4 SLC2A4 SCARA3 SCARA3
"SYNGR2" - synaptogyrin 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYNGR2synaptogyrin 2 (224 aa)    
Predicted Functional Partners:
TMC8
transmembrane channel-like 8; Probable ion channel (By similarity) (726 aa)
            score_image   0.862
TMC6
transmembrane channel-like 6; Probable ion channel (By similarity) (805 aa)
            score_image   0.862
SYNPR
synaptoporin; Intrinsic membrane protein of small synaptic vesicles. Probable vesicular channel protein (By similarity) (285 aa)
            score_image   0.741
UBC
ubiquitin C (685 aa)
        score_image       0.721
TK1
thymidine kinase 1, soluble (234 aa)
            score_image   0.681
FATE1
fetal and adult testis expressed 1 (183 aa)
        score_image       0.633
SCARA3
scavenger receptor class A, member 3; Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation (606 aa)
        score_image       0.613
CANX
calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at [...] (592 aa)
            score_image   0.610
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4; Insulin-regulated facilitative glucose transporter (509 aa)
            score_image   0.581
VTI1A
vesicle transport through interaction with t-SNAREs homolog 1A (yeast); V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non- conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with [...] (217 aa)
            score_image   0.475
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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