node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKAP3 | ROPN1 | ENSP00000228850 | ENSP00000184183 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | rhophilin associated tail protein 1 | 0.937 |
AKAP3 | ROPN1L | ENSP00000228850 | ENSP00000274134 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | rhophilin associated tail protein 1-like | 0.936 |
AKAP3 | SPA17 | ENSP00000228850 | ENSP00000227135 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) | 0.938 |
AKAP7 | ROPN1 | ENSP00000405252 | ENSP00000184183 | A kinase (PRKA) anchor protein 7; Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium | rhophilin associated tail protein 1 | 0.452 |
AKAP7 | SPA17 | ENSP00000405252 | ENSP00000227135 | A kinase (PRKA) anchor protein 7; Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium | sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) | 0.786 |
GAS2 | RASL10A | ENSP00000278187 | ENSP00000216101 | growth arrest-specific 2; May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity) | RAS-like, family 10, member A; Potent inhibitor of cellular proliferation | 0.749 |
GAS2 | SPA17 | ENSP00000278187 | ENSP00000227135 | growth arrest-specific 2; May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity) | sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) | 0.742 |
GAS2L1 | RASL10A | ENSP00000344012 | ENSP00000216101 | growth arrest-specific 2 like 1; Seems to be involved in the cross-linking of microtubules and microfilaments | RAS-like, family 10, member A; Potent inhibitor of cellular proliferation | 0.868 |
GAS2L1 | SPA17 | ENSP00000344012 | ENSP00000227135 | growth arrest-specific 2 like 1; Seems to be involved in the cross-linking of microtubules and microfilaments | sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) | 0.747 |
GAS2L2 | RASL10A | ENSP00000254466 | ENSP00000216101 | growth arrest-specific 2 like 2; Seems to be involved in the cross-linking of microtubules and microfilaments | RAS-like, family 10, member A; Potent inhibitor of cellular proliferation | 0.817 |
GAS2L2 | SPA17 | ENSP00000254466 | ENSP00000227135 | growth arrest-specific 2 like 2; Seems to be involved in the cross-linking of microtubules and microfilaments | sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) | 0.757 |
PRSS50 | SPA17 | ENSP00000326598 | ENSP00000227135 | protease, serine, 50; May be involved in proteolysis through its threonine endopeptidase activity | sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) | 0.727 |
RASL10A | GAS2 | ENSP00000216101 | ENSP00000278187 | RAS-like, family 10, member A; Potent inhibitor of cellular proliferation | growth arrest-specific 2; May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity) | 0.749 |
RASL10A | GAS2L1 | ENSP00000216101 | ENSP00000344012 | RAS-like, family 10, member A; Potent inhibitor of cellular proliferation | growth arrest-specific 2 like 1; Seems to be involved in the cross-linking of microtubules and microfilaments | 0.868 |
RASL10A | GAS2L2 | ENSP00000216101 | ENSP00000254466 | RAS-like, family 10, member A; Potent inhibitor of cellular proliferation | growth arrest-specific 2 like 2; Seems to be involved in the cross-linking of microtubules and microfilaments | 0.817 |
RASL10A | SPA17 | ENSP00000216101 | ENSP00000227135 | RAS-like, family 10, member A; Potent inhibitor of cellular proliferation | sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) | 0.754 |
ROPN1 | AKAP3 | ENSP00000184183 | ENSP00000228850 | rhophilin associated tail protein 1 | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | 0.937 |
ROPN1 | AKAP7 | ENSP00000184183 | ENSP00000405252 | rhophilin associated tail protein 1 | A kinase (PRKA) anchor protein 7; Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium | 0.452 |
ROPN1 | SPA17 | ENSP00000184183 | ENSP00000227135 | rhophilin associated tail protein 1 | sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) | 0.985 |
ROPN1L | AKAP3 | ENSP00000274134 | ENSP00000228850 | rhophilin associated tail protein 1-like | A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction | 0.936 |