PARP11 protein (Homo sapiens) - STRING network view

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Score

PARP11

poly (ADP-ribose) polymerase family, member 11 (338 aa)

Predicted Functional Partners:

DCAF11

0.740

OTUD4

0.740

LYZ

0.740

RNF114

0.740

GTPBP3

0.692

PSMC2

0.692

CRLF3

0.646

CCDC111

0.628

ARMC9

0.605

RHBDD1

0.602

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMC9	PARP11	ENSP00000258417	ENSP00000228820	armadillo repeat containing 9	poly (ADP-ribose) polymerase family, member 11	0.605
CCDC111	CRLF3	ENSP00000313816	ENSP00000318804	coiled-coil domain containing 111	cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression	0.633
CCDC111	PARP11	ENSP00000313816	ENSP00000228820	coiled-coil domain containing 111	poly (ADP-ribose) polymerase family, member 11	0.628
CCDC111	RHBDD1	ENSP00000313816	ENSP00000344779	coiled-coil domain containing 111	rhomboid domain containing 1; Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the trans [...]	0.618
CRLF3	CCDC111	ENSP00000318804	ENSP00000313816	cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression	coiled-coil domain containing 111	0.633
CRLF3	PARP11	ENSP00000318804	ENSP00000228820	cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression	poly (ADP-ribose) polymerase family, member 11	0.646
CRLF3	RHBDD1	ENSP00000318804	ENSP00000344779	cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression	rhomboid domain containing 1; Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the trans [...]	0.594
DCAF11	PARP11	ENSP00000415556	ENSP00000228820	DDB1 and CUL4 associated factor 11	poly (ADP-ribose) polymerase family, member 11	0.740
GTPBP3	PARP11	ENSP00000351644	ENSP00000228820	GTP binding protein 3 (mitochondrial)	poly (ADP-ribose) polymerase family, member 11	0.692
GTPBP3	PSMC2	ENSP00000351644	ENSP00000292644	GTP binding protein 3 (mitochondrial)	proteasome (prosome, macropain) 26S subunit, ATPase, 2; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation	0.857
LYZ	PARP11	ENSP00000261267	ENSP00000228820	lysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents	poly (ADP-ribose) polymerase family, member 11	0.740
OTUD4	PARP11	ENSP00000409279	ENSP00000228820	OTU domain containing 4	poly (ADP-ribose) polymerase family, member 11	0.740
PARP11	ARMC9	ENSP00000228820	ENSP00000258417	poly (ADP-ribose) polymerase family, member 11	armadillo repeat containing 9	0.605
PARP11	CCDC111	ENSP00000228820	ENSP00000313816	poly (ADP-ribose) polymerase family, member 11	coiled-coil domain containing 111	0.628
PARP11	CRLF3	ENSP00000228820	ENSP00000318804	poly (ADP-ribose) polymerase family, member 11	cytokine receptor-like factor 3; May play a role in the negative regulation of cell cycle progression	0.646
PARP11	DCAF11	ENSP00000228820	ENSP00000415556	poly (ADP-ribose) polymerase family, member 11	DDB1 and CUL4 associated factor 11	0.740
PARP11	GTPBP3	ENSP00000228820	ENSP00000351644	poly (ADP-ribose) polymerase family, member 11	GTP binding protein 3 (mitochondrial)	0.692
PARP11	LYZ	ENSP00000228820	ENSP00000261267	poly (ADP-ribose) polymerase family, member 11	lysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents	0.740
PARP11	OTUD4	ENSP00000228820	ENSP00000409279	poly (ADP-ribose) polymerase family, member 11	OTU domain containing 4	0.740
PARP11	PSMC2	ENSP00000228820	ENSP00000292644	poly (ADP-ribose) polymerase family, member 11	proteasome (prosome, macropain) 26S subunit, ATPase, 2; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation	0.692

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