AKAP3 protein (Homo sapiens) - STRING network view

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AKAP3

A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction (853 aa)

Predicted Functional Partners:

CABYR

0.970

SPA17

0.938

ROPN1

0.937

ROPN1L

0.936

PRKAR2A

0.918

CCDC54

0.913

PDE4A

0.825

NDUFAF3

0.669

AKAP4

0.639

AKAP1

0.608

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP1	AKAP3	ENSP00000337736	ENSP00000228850	A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	0.608
AKAP1	CABYR	ENSP00000337736	ENSP00000432870	A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane	calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium	0.608
AKAP1	PDE4A	ENSP00000337736	ENSP00000270474	A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane	phosphodiesterase 4A, cAMP-specific	0.502
AKAP1	PRKAR2A	ENSP00000337736	ENSP00000265563	A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane	protein kinase, cAMP-dependent, regulatory, type II, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase	0.999
AKAP3	AKAP1	ENSP00000228850	ENSP00000337736	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane	0.608
AKAP3	AKAP4	ENSP00000228850	ENSP00000351327	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	A kinase (PRKA) anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility	0.639
AKAP3	CABYR	ENSP00000228850	ENSP00000432870	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium	0.970
AKAP3	CCDC54	ENSP00000228850	ENSP00000261058	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	coiled-coil domain containing 54	0.913
AKAP3	NDUFAF3	ENSP00000228850	ENSP00000323076	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	NADH dehydrogenase (ubiquinone) complex I, assembly factor 3; Essential factor for the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I)	0.669
AKAP3	PDE4A	ENSP00000228850	ENSP00000270474	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	phosphodiesterase 4A, cAMP-specific	0.825
AKAP3	PRKAR2A	ENSP00000228850	ENSP00000265563	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	protein kinase, cAMP-dependent, regulatory, type II, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase	0.918
AKAP3	ROPN1	ENSP00000228850	ENSP00000184183	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	rhophilin associated tail protein 1	0.937
AKAP3	ROPN1L	ENSP00000228850	ENSP00000274134	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	rhophilin associated tail protein 1-like	0.936
AKAP3	SPA17	ENSP00000228850	ENSP00000227135	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity)	0.938
AKAP4	AKAP3	ENSP00000351327	ENSP00000228850	A kinase (PRKA) anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	0.639
AKAP4	PRKAR2A	ENSP00000351327	ENSP00000265563	A kinase (PRKA) anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility	protein kinase, cAMP-dependent, regulatory, type II, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase	0.720
AKAP4	ROPN1	ENSP00000351327	ENSP00000184183	A kinase (PRKA) anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility	rhophilin associated tail protein 1	0.482
CABYR	AKAP1	ENSP00000432870	ENSP00000337736	calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium	A kinase (PRKA) anchor protein 1; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane	0.608
CABYR	AKAP3	ENSP00000432870	ENSP00000228850	calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium	A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction	0.970
CABYR	CCDC54	ENSP00000432870	ENSP00000261058	calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium	coiled-coil domain containing 54	0.581

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