node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ICT1 | MRPL24 | ENSP00000301585 | ENSP00000354525 | immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes | mitochondrial ribosomal protein L24 | 0.495 |
ICT1 | MRPL38 | ENSP00000301585 | ENSP00000308275 | immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes | mitochondrial ribosomal protein L38 | 0.455 |
ICT1 | MRPL40 | ENSP00000301585 | ENSP00000333401 | immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes | mitochondrial ribosomal protein L40 | 0.662 |
ICT1 | MRPL51 | ENSP00000301585 | ENSP00000229238 | immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes | mitochondrial ribosomal protein L51 | 0.934 |
ICT1 | MRPL52 | ENSP00000301585 | ENSP00000347277 | immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes | mitochondrial ribosomal protein L52 | 0.910 |
ICT1 | MRPL55 | ENSP00000301585 | ENSP00000355692 | immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes | mitochondrial ribosomal protein L55 | 0.938 |
ICT1 | TP53I3 | ENSP00000301585 | ENSP00000238721 | immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes | tumor protein p53 inducible protein 3; May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro) | 0.922 |
MRPL21 | MRPL24 | ENSP00000354580 | ENSP00000354525 | mitochondrial ribosomal protein L21 | mitochondrial ribosomal protein L24 | 0.951 |
MRPL21 | MRPL38 | ENSP00000354580 | ENSP00000308275 | mitochondrial ribosomal protein L21 | mitochondrial ribosomal protein L38 | 0.991 |
MRPL21 | MRPL40 | ENSP00000354580 | ENSP00000333401 | mitochondrial ribosomal protein L21 | mitochondrial ribosomal protein L40 | 0.942 |
MRPL21 | MRPL51 | ENSP00000354580 | ENSP00000229238 | mitochondrial ribosomal protein L21 | mitochondrial ribosomal protein L51 | 0.973 |
MRPL24 | ICT1 | ENSP00000354525 | ENSP00000301585 | mitochondrial ribosomal protein L24 | immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes | 0.495 |
MRPL24 | MRPL21 | ENSP00000354525 | ENSP00000354580 | mitochondrial ribosomal protein L24 | mitochondrial ribosomal protein L21 | 0.951 |
MRPL24 | MRPL37 | ENSP00000354525 | ENSP00000354086 | mitochondrial ribosomal protein L24 | mitochondrial ribosomal protein L37 | 0.951 |
MRPL24 | MRPL40 | ENSP00000354525 | ENSP00000333401 | mitochondrial ribosomal protein L24 | mitochondrial ribosomal protein L40 | 0.932 |
MRPL24 | MRPL44 | ENSP00000354525 | ENSP00000258383 | mitochondrial ribosomal protein L24 | mitochondrial ribosomal protein L44; Component of the 39S subunit of mitochondrial ribosome | 0.923 |
MRPL24 | MRPL51 | ENSP00000354525 | ENSP00000229238 | mitochondrial ribosomal protein L24 | mitochondrial ribosomal protein L51 | 0.935 |
MRPL24 | MRPL55 | ENSP00000354525 | ENSP00000355692 | mitochondrial ribosomal protein L24 | mitochondrial ribosomal protein L55 | 0.424 |
MRPL37 | MRPL24 | ENSP00000354086 | ENSP00000354525 | mitochondrial ribosomal protein L37 | mitochondrial ribosomal protein L24 | 0.951 |
MRPL37 | MRPL38 | ENSP00000354086 | ENSP00000308275 | mitochondrial ribosomal protein L37 | mitochondrial ribosomal protein L38 | 0.932 |