node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASNA1 | COG6 | ENSP00000349887 | ENSP00000397441 | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane pro [...] | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | 0.499 |
ASNA1 | GOLT1B | ENSP00000349887 | ENSP00000229314 | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane pro [...] | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | 0.667 |
ASNA1 | UBC | ENSP00000349887 | ENSP00000344818 | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane pro [...] | ubiquitin C | 0.863 |
ASUN | GOLT1B | ENSP00000261191 | ENSP00000229314 | asunder, spermatogenesis regulator homolog (Drosphila); Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | 0.506 |
ASUN | UBC | ENSP00000261191 | ENSP00000344818 | asunder, spermatogenesis regulator homolog (Drosphila); Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis | ubiquitin C | 0.692 |
COG6 | ASNA1 | ENSP00000397441 | ENSP00000349887 | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane pro [...] | 0.499 |
COG6 | GOLT1B | ENSP00000397441 | ENSP00000229314 | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | 0.575 |
COG6 | SFT2D1 | ENSP00000397441 | ENSP00000354590 | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | SFT2 domain containing 1; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) | 0.583 |
COG6 | SFT2D2 | ENSP00000397441 | ENSP00000271375 | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | SFT2 domain containing 2; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) | 0.583 |
COG6 | SFT2D3 | ENSP00000397441 | ENSP00000310803 | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | SFT2 domain containing 3; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) | 0.724 |
GOLT1B | ASNA1 | ENSP00000229314 | ENSP00000349887 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane pro [...] | 0.667 |
GOLT1B | ASUN | ENSP00000229314 | ENSP00000261191 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | asunder, spermatogenesis regulator homolog (Drosphila); Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis | 0.506 |
GOLT1B | COG6 | ENSP00000229314 | ENSP00000397441 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) | 0.575 |
GOLT1B | MDFIC | ENSP00000229314 | ENSP00000257724 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | MyoD family inhibitor domain containing; Acts as a transcriptional activator or repressor. Inhibits the transcriptional activation of Zic family proteins ZIC1, ZIC2 and ZIC3. Retains nuclear Zic proteins ZIC1, ZIC2 and ZIC3 in the cytoplasm. Modulates the expression from both cellular and viral promoters. Down-regulates Tat-dependent transcription of the human immunodeficiency virus type 1 (HIV-1) LTR by interacting with HIV-1 Tat and Rev and impairing their nuclear import, probably by rendering the NLS domains inaccessible to importin- beta. Also stimulates activation of human T-cell [...] | 0.501 |
GOLT1B | SFT2D1 | ENSP00000229314 | ENSP00000354590 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | SFT2 domain containing 1; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) | 0.665 |
GOLT1B | SFT2D2 | ENSP00000229314 | ENSP00000271375 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | SFT2 domain containing 2; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) | 0.665 |
GOLT1B | SFT2D3 | ENSP00000229314 | ENSP00000310803 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | SFT2 domain containing 3; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) | 0.824 |
GOLT1B | SLC30A7 | ENSP00000229314 | ENSP00000350278 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) | 0.629 |
GOLT1B | SYT9 | ENSP00000229314 | ENSP00000324419 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | synaptotagmin IX; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis | 0.495 |
GOLT1B | UBC | ENSP00000229314 | ENSP00000344818 | golgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | ubiquitin C | 0.804 |