SLC44A4 protein (Homo sapiens) - STRING network view

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SLC44A4

solute carrier family 44, member 4 (710 aa)

Predicted Functional Partners:

TMEM163

0.592

XKR3

0.564

FAM181A

0.512

WDR73

0.510

C10orf67

0.507

NABP1

0.483

NABP2

0.483

PABPC1L2B

0.447

PABPC1L2A

0.447

PABPC4

0.447

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf67	SLC44A4	ENSP00000321464	ENSP00000229729	chromosome 10 open reading frame 67	solute carrier family 44, member 4	0.507
C10orf67	WDR73	ENSP00000321464	ENSP00000387982	chromosome 10 open reading frame 67	WD repeat domain 73	0.563
FAM181A	SLC44A4	ENSP00000267594	ENSP00000229729	family with sequence similarity 181, member A	solute carrier family 44, member 4	0.512
NABP1	NABP2	ENSP00000403683	ENSP00000267023	nucleic acid binding protein 1; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of d [...]	nucleic acid binding protein 2; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of d [...]	0.905
NABP1	SLC44A4	ENSP00000403683	ENSP00000229729	nucleic acid binding protein 1; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of d [...]	solute carrier family 44, member 4	0.483
NABP2	NABP1	ENSP00000267023	ENSP00000403683	nucleic acid binding protein 2; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of d [...]	nucleic acid binding protein 1; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of d [...]	0.905
NABP2	SLC44A4	ENSP00000267023	ENSP00000229729	nucleic acid binding protein 2; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of d [...]	solute carrier family 44, member 4	0.483
PABPC1L2A	SLC44A4	ENSP00000362618	ENSP00000229729	poly(A) binding protein, cytoplasmic 1-like 2A	solute carrier family 44, member 4	0.447
PABPC1L2B	SLC44A4	ENSP00000362621	ENSP00000229729	poly(A) binding protein, cytoplasmic 1-like 2B	solute carrier family 44, member 4	0.447
PABPC4	SLC44A4	ENSP00000361949	ENSP00000229729	poly(A) binding protein, cytoplasmic 4 (inducible form); Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity)	solute carrier family 44, member 4	0.447
SLC44A4	C10orf67	ENSP00000229729	ENSP00000321464	solute carrier family 44, member 4	chromosome 10 open reading frame 67	0.507
SLC44A4	FAM181A	ENSP00000229729	ENSP00000267594	solute carrier family 44, member 4	family with sequence similarity 181, member A	0.512
SLC44A4	NABP1	ENSP00000229729	ENSP00000403683	solute carrier family 44, member 4	nucleic acid binding protein 1; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of d [...]	0.483
SLC44A4	NABP2	ENSP00000229729	ENSP00000267023	solute carrier family 44, member 4	nucleic acid binding protein 2; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of d [...]	0.483
SLC44A4	PABPC1L2A	ENSP00000229729	ENSP00000362618	solute carrier family 44, member 4	poly(A) binding protein, cytoplasmic 1-like 2A	0.447
SLC44A4	PABPC1L2B	ENSP00000229729	ENSP00000362621	solute carrier family 44, member 4	poly(A) binding protein, cytoplasmic 1-like 2B	0.447
SLC44A4	PABPC4	ENSP00000229729	ENSP00000361949	solute carrier family 44, member 4	poly(A) binding protein, cytoplasmic 4 (inducible form); Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity)	0.447
SLC44A4	TMEM163	ENSP00000229729	ENSP00000281924	solute carrier family 44, member 4	transmembrane protein 163; May bind zinc and other divalent cations and recruit them to vesicular organelles (By similarity)	0.592
SLC44A4	WDR73	ENSP00000229729	ENSP00000387982	solute carrier family 44, member 4	WD repeat domain 73	0.510
SLC44A4	XKR3	ENSP00000229729	ENSP00000331704	solute carrier family 44, member 4	XK, Kell blood group complex subunit-related family, member 3	0.564

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