node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARID2 | POU4F3 | ENSP00000335044 | ENSP00000230732 | AT rich interactive domain 2 (ARID, RFX-like) | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.612 |
ARID3A | POU4F3 | ENSP00000263620 | ENSP00000230732 | AT rich interactive domain 3A (BRIGHT-like); Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.733 |
ARID3B | POU4F3 | ENSP00000343126 | ENSP00000230732 | AT rich interactive domain 3B (BRIGHT-like); Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.733 |
ARID3C | POU4F3 | ENSP00000368189 | ENSP00000230732 | AT rich interactive domain 3C (BRIGHT-like) | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.733 |
ATOH1 | BARHL1 | ENSP00000302216 | ENSP00000263610 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | BarH-like homeobox 1 | 0.591 |
ATOH1 | GFI1 | ENSP00000302216 | ENSP00000294702 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | growth factor independent 1 transcription repressor; Transcription repressor essential for hematopoiesis. Functions in a cell-context and development-specific manner. Binds to 5’-TAAATCAC[AT]GCA-3’ in the promoter region of a large number of genes. Component of several complexes, including the EHMT2- GFI1-HDAC1, AJUBA-GFI1-HDAC1 and RCOR-GFI-KDM1A-HDAC complexes, that suppress, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Regulates neutrophil differentiation, promotes proliferation of lymphoid cells, and is required fo [...] | 0.590 |
ATOH1 | POU4F3 | ENSP00000302216 | ENSP00000230732 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.626 |
ATOH7 | POU4F3 | ENSP00000362777 | ENSP00000230732 | atonal homolog 7 (Drosophila); Transcription factor involved in the differentiation of retinal ganglion cells (By similarity) | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.641 |
BARHL1 | ATOH1 | ENSP00000263610 | ENSP00000302216 | BarH-like homeobox 1 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | 0.591 |
BARHL1 | POU4F3 | ENSP00000263610 | ENSP00000230732 | BarH-like homeobox 1 | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.724 |
GFI1 | ATOH1 | ENSP00000294702 | ENSP00000302216 | growth factor independent 1 transcription repressor; Transcription repressor essential for hematopoiesis. Functions in a cell-context and development-specific manner. Binds to 5’-TAAATCAC[AT]GCA-3’ in the promoter region of a large number of genes. Component of several complexes, including the EHMT2- GFI1-HDAC1, AJUBA-GFI1-HDAC1 and RCOR-GFI-KDM1A-HDAC complexes, that suppress, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Regulates neutrophil differentiation, promotes proliferation of lymphoid cells, and is required fo [...] | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | 0.590 |
GFI1 | POU4F3 | ENSP00000294702 | ENSP00000230732 | growth factor independent 1 transcription repressor; Transcription repressor essential for hematopoiesis. Functions in a cell-context and development-specific manner. Binds to 5’-TAAATCAC[AT]GCA-3’ in the promoter region of a large number of genes. Component of several complexes, including the EHMT2- GFI1-HDAC1, AJUBA-GFI1-HDAC1 and RCOR-GFI-KDM1A-HDAC complexes, that suppress, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Regulates neutrophil differentiation, promotes proliferation of lymphoid cells, and is required fo [...] | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.751 |
LCOR | POU4F3 | ENSP00000348298 | ENSP00000230732 | ligand dependent nuclear receptor corepressor; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.702 |
LCORL | POU4F3 | ENSP00000371661 | ENSP00000230732 | ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity) | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.642 |
POU4F3 | ARID2 | ENSP00000230732 | ENSP00000335044 | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | AT rich interactive domain 2 (ARID, RFX-like) | 0.612 |
POU4F3 | ARID3A | ENSP00000230732 | ENSP00000263620 | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | AT rich interactive domain 3A (BRIGHT-like); Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation | 0.733 |
POU4F3 | ARID3B | ENSP00000230732 | ENSP00000343126 | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | AT rich interactive domain 3B (BRIGHT-like); Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A | 0.733 |
POU4F3 | ARID3C | ENSP00000230732 | ENSP00000368189 | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | AT rich interactive domain 3C (BRIGHT-like) | 0.733 |
POU4F3 | ATOH1 | ENSP00000230732 | ENSP00000302216 | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | 0.626 |
POU4F3 | ATOH7 | ENSP00000230732 | ENSP00000362777 | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | atonal homolog 7 (Drosophila); Transcription factor involved in the differentiation of retinal ganglion cells (By similarity) | 0.641 |