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STRINGSTRING
PRSS3 PRSS3 RUNX1T1 RUNX1T1 CTCF CTCF CDR1 CDR1 ZMYND10 ZMYND10 NPRL2 NPRL2 SASS6 SASS6 TUSC2 TUSC2 IFT43 IFT43 CYB561D2 CYB561D2 LRRC6 LRRC6
"ZMYND10" - zinc finger, MYND-type containing 10 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ZMYND10zinc finger, MYND-type containing 10 (440 aa)    
Predicted Functional Partners:
LRRC6
leucine rich repeat containing 6; May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility (466 aa)
        score_image   score_image   0.869
PRSS3
protease, serine, 3; Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5 (304 aa)
            score_image   0.811
CTCF
CCCTC-binding factor (zinc finger protein); Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo devel [...] (727 aa)
            score_image   0.803
CYB561D2
cytochrome b-561 domain containing 2 (222 aa)
            score_image   0.793
NPRL2
nitrogen permease regulator-like 2 (S. cerevisiae); Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs (380 aa)
            score_image   0.728
TUSC2
tumor suppressor candidate 2; May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells (110 aa)
            score_image   0.726
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (615 aa)
            score_image   0.683
CDR1
cerebellar degeneration-related protein 1, 34kDa (262 aa)
        score_image       0.608
SASS6
spindle assembly 6 homolog (C. elegans); Required for centrosome duplication. Overexpression results in excess foci-bearing centriolar markers (657 aa)
            score_image   0.587
IFT43
intraflagellar transport 43 homolog (Chlamydomonas); Component of IFT complex A (IFT-A) involved in retrograde ciliary transport along microtubules from the ciliary tip to the base (213 aa)
        score_image       0.581
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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