FAM82A1 protein (Homo sapiens) - STRING network view

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Score

FAM82A1

family with sequence similarity 82, member A1 (573 aa)

Predicted Functional Partners:

VAPB

0.590

PTPN2

0.561

CAV3

0.487

PTPN1

0.440

FAM3A

0.407

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV3	FAM82A1	ENSP00000341940	ENSP00000234195	caveolin 3; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress	family with sequence similarity 82, member A1	0.487
CAV3	PTPN1	ENSP00000341940	ENSP00000360683	caveolin 3; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress	protein tyrosine phosphatase, non-receptor type 1; Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion	0.786
CAV3	PTPN2	ENSP00000341940	ENSP00000311857	caveolin 3; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress	protein tyrosine phosphatase, non-receptor type 2	0.689
FAM3A	FAM82A1	ENSP00000352955	ENSP00000234195	family with sequence similarity 3, member A; May act as a defensin against invading fungal microorganisms	family with sequence similarity 82, member A1	0.407
FAM82A1	CAV3	ENSP00000234195	ENSP00000341940	family with sequence similarity 82, member A1	caveolin 3; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress	0.487
FAM82A1	FAM3A	ENSP00000234195	ENSP00000352955	family with sequence similarity 82, member A1	family with sequence similarity 3, member A; May act as a defensin against invading fungal microorganisms	0.407
FAM82A1	PTPN1	ENSP00000234195	ENSP00000360683	family with sequence similarity 82, member A1	protein tyrosine phosphatase, non-receptor type 1; Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion	0.440
FAM82A1	PTPN2	ENSP00000234195	ENSP00000311857	family with sequence similarity 82, member A1	protein tyrosine phosphatase, non-receptor type 2	0.561
FAM82A1	VAPB	ENSP00000234195	ENSP00000417175	family with sequence similarity 82, member A1	VAMP (vesicle-associated membrane protein)-associated protein B and C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation	0.590
PTPN1	CAV3	ENSP00000360683	ENSP00000341940	protein tyrosine phosphatase, non-receptor type 1; Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion	caveolin 3; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress	0.786
PTPN1	FAM82A1	ENSP00000360683	ENSP00000234195	protein tyrosine phosphatase, non-receptor type 1; Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion	family with sequence similarity 82, member A1	0.440
PTPN2	CAV3	ENSP00000311857	ENSP00000341940	protein tyrosine phosphatase, non-receptor type 2	caveolin 3; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress	0.689
PTPN2	FAM82A1	ENSP00000311857	ENSP00000234195	protein tyrosine phosphatase, non-receptor type 2	family with sequence similarity 82, member A1	0.561
VAPB	FAM82A1	ENSP00000417175	ENSP00000234195	VAMP (vesicle-associated membrane protein)-associated protein B and C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation	family with sequence similarity 82, member A1	0.590

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