SLC1A4 protein (Homo sapiens) - STRING network view

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SLC1A4

solute carrier family 1 (glutamate/neutral amino acid transporter), member 4; Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence (532 aa)

Predicted Functional Partners:

SELV

0.818

GPR83

0.811

UBC

0.807

AVP

0.802

MEST

0.757

AVEN

0.756

HELT

0.726

STYK1

0.726

ERVW-1

0.715

OVGP1

0.704

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AVEN	GPR83	ENSP00000306822	ENSP00000243673	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	0.875
AVEN	HELT	ENSP00000306822	ENSP00000343464	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	helt bHLH transcription factor; Transcriptional repressor which binds preferentially to the canonical E box sequence 5’-CACGCG-3’ (By similarity)	0.870
AVEN	MEST	ENSP00000306822	ENSP00000223215	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	mesoderm specific transcript homolog (mouse)	0.870
AVEN	OVGP1	ENSP00000306822	ENSP00000358747	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	oviductal glycoprotein 1, 120kDa; Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development	0.814
AVEN	SELV	ENSP00000306822	ENSP00000333956	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	selenoprotein V ; May be involved in a redox-related process (Potential)	0.909
AVEN	SLC1A4	ENSP00000306822	ENSP00000234256	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4; Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence	0.756
AVEN	STYK1	ENSP00000306822	ENSP00000075503	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	serine/threonine/tyrosine kinase 1; Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3’-kinases (PI3K) pathways (By similarity)	0.824
AVEN	UBC	ENSP00000306822	ENSP00000344818	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	ubiquitin C	0.727
AVP	SLC1A4	ENSP00000369647	ENSP00000234256	arginine vasopressin; Neurophysin 2 specifically binds vasopressin	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4; Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence	0.802
ERVW-1	SLC1A4	ENSP00000419945	ENSP00000234256	endogenous retrovirus group W, member 1; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4; Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence	0.715
GPR83	AVEN	ENSP00000243673	ENSP00000306822	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	0.875
GPR83	HELT	ENSP00000243673	ENSP00000343464	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	helt bHLH transcription factor; Transcriptional repressor which binds preferentially to the canonical E box sequence 5’-CACGCG-3’ (By similarity)	0.874
GPR83	MEST	ENSP00000243673	ENSP00000223215	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	mesoderm specific transcript homolog (mouse)	0.885
GPR83	OVGP1	ENSP00000243673	ENSP00000358747	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	oviductal glycoprotein 1, 120kDa; Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development	0.824
GPR83	SELV	ENSP00000243673	ENSP00000333956	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	selenoprotein V ; May be involved in a redox-related process (Potential)	0.909
GPR83	SLC1A4	ENSP00000243673	ENSP00000234256	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4; Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence	0.811
GPR83	STYK1	ENSP00000243673	ENSP00000075503	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	serine/threonine/tyrosine kinase 1; Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3’-kinases (PI3K) pathways (By similarity)	0.871
HELT	AVEN	ENSP00000343464	ENSP00000306822	helt bHLH transcription factor; Transcriptional repressor which binds preferentially to the canonical E box sequence 5’-CACGCG-3’ (By similarity)	apoptosis, caspase activation inhibitor; Protects against apoptosis mediated by Apaf-1	0.870
HELT	GPR83	ENSP00000343464	ENSP00000243673	helt bHLH transcription factor; Transcriptional repressor which binds preferentially to the canonical E box sequence 5’-CACGCG-3’ (By similarity)	G protein-coupled receptor 83; Orphan receptor. Could be a neuropeptide Y receptor	0.874
HELT	MEST	ENSP00000343464	ENSP00000223215	helt bHLH transcription factor; Transcriptional repressor which binds preferentially to the canonical E box sequence 5’-CACGCG-3’ (By similarity)	mesoderm specific transcript homolog (mouse)	0.878

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