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STRINGSTRING
LIPK LIPK DTNB DTNB DTNA DTNA SGCZ SGCZ SOGA1 SOGA1 KHK KHK KIF19 KIF19 C14orf119 C14orf119 UBC UBC FLT1 FLT1 C2orf29 C2orf29
"SOGA1" - suppressor of glucose, autophagy associated 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
SOGA1suppressor of glucose, autophagy associated 1; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner (By similarity) (1661 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.849
C14orf119
chromosome 14 open reading frame 119 (140 aa)
            score_image   0.675
DTNB
dystrobrevin, beta (627 aa)
        score_image       0.634
DTNA
dystrobrevin, alpha (743 aa)
        score_image       0.634
KIF19
kinesin family member 19; Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips (By similarity) (998 aa)
            score_image   0.628
SGCZ
sarcoglycan, zeta; Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. May play a role in the maintenance of striated muscle membrane stability (By similarity) (312 aa)
            score_image   0.625
KHK
ketohexokinase (fructokinase) (298 aa)
            score_image   0.589
FLT1
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (1338 aa)
        score_image   score_image   0.576
C2orf29
chromosome 2 open reading frame 29; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function (510 aa)
            score_image   0.538
LIPK
lipase, family member K; Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (399 aa)
            score_image   0.487
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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