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NIP7 NIP7 KIAA0020 KIAA0020 DDX27 DDX27 NOP2 NOP2 PES1 PES1 RPF1 RPF1 DDX54 DDX54 CEBPZ CEBPZ DDX55 DDX55 MKI67IP MKI67IP WDR12 WDR12
"DDX55" - DEAD in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
DDX55DEAD (Asp-Glu-Ala-Asp) box polypeptide 55; Probable ATP-binding RNA helicase (600 aa)    
Predicted Functional Partners:
WDR12
WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome (423 aa)
      score_image score_image   score_image   0.984
NOP2
NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase (808 aa)
      score_image score_image   score_image   0.983
PES1
pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome (588 aa)
      score_image score_image   score_image   0.981
KIAA0020
KIAA0020 (648 aa)
      score_image score_image       0.976
DDX54
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors (882 aa)
    score_image score_image score_image   score_image score_image 0.976
NIP7
nuclear import 7 homolog (S. cerevisiae); Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly (180 aa)
      score_image score_image   score_image   0.970
RPF1
ribosome production factor 1 homolog (S. cerevisiae); May be required for ribosome biogenesis (349 aa)
      score_image score_image       0.967
MKI67IP
MKI67 (FHA domain) interacting nucleolar phosphoprotein (293 aa)
      score_image score_image   score_image   0.967
DDX27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 (796 aa)
    score_image score_image score_image   score_image score_image 0.965
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta; Stimulates transcription from the HSP70 promoter (1054 aa)
      score_image score_image   score_image   0.965
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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