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ALAS1 ALAS1 MORN2 MORN2 ZDBF2 ZDBF2 C1orf109 C1orf109 ADCK1 ADCK1 COQ7 COQ7 COQ5 COQ5 COQ9 COQ9 COQ4 COQ4 COQ3 COQ3 CPT1A CPT1A
"ADCK1" - aarF domain containing kinase 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADCK1aarF domain containing kinase 1; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (523 aa)    
Predicted Functional Partners:
COQ5
coenzyme Q5 homolog, methyltransferase (S. cerevisiae); Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) (327 aa)
score_image     score_image score_image   score_image   0.716
ZDBF2
zinc finger, DBF-type containing 2 (2354 aa)
            score_image   0.532
C1orf109
chromosome 1 open reading frame 109 (203 aa)
            score_image   0.507
COQ4
coenzyme Q4 homolog (S. cerevisiae); Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides (265 aa)
        score_image   score_image   0.486
COQ3
coenzyme Q3 homolog, methyltransferase (S. cerevisiae) (369 aa)
        score_image   score_image   0.466
ALAS1
aminolevulinate, delta-, synthase 1 (640 aa)
            score_image   0.454
MORN2
MORN repeat containing 2 (79 aa)
            score_image   0.452
CPT1A
carnitine palmitoyltransferase 1A (liver); Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism (773 aa)
            score_image   0.441
COQ9
coenzyme Q9 homolog (S. cerevisiae); Involved in the biosynthesis of coenzyme Q (By similarity) (318 aa)
        score_image   score_image   0.436
COQ7
coenzyme Q7 homolog, ubiquinone (yeast); Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator (By similarity) (217 aa)
        score_image   score_image   0.417
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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